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https://academic.oup.com/jac/article/54/4/761/763466
Oct 01, 2004 · Wheat germ agglutinin (WGA) is finding wide application in drug delivery research because it is one of the least immunogenic lectins. 6 Also, WGA is known to have its receptors on intestinal 7 as well as alveolar epithelium, 8 thus potentiating its use for …Author: Anjali Sharma, Sadhna Sharma, G. K. Khuller
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2440032/
As the smallest lectin, odorranalectin has potential for drug delivery and targeting because of its several unique characters. Firstly, odorranalectin is composed of only 17 amino acid residues with a molecular weight of 1887.9 Da and has a single disulfide bridge that makes it easy to manipulate and develop a drug targeting system.Author: Jianxu Li, Jianxu Li, Hongbing Wu, Jing Hong, Xueqing Xu, Xueqing Xu, Hailong Yang, Bingxian Wu, Yip...
https://www.sciencedirect.com/science/article/pii/S0169409X0300231X
Many lectin-binding studies used fixed (processed) histological sections and binding across cut cells is considered, making it difficult to identify the purely cell surface binding that would be required for lectin-targeted drug delivery.Author: John D. Smart
https://www.ncbi.nlm.nih.gov/pubmed/10699266
Mar 01, 2000 · Lectin-mediated drug delivery: the second generation of bioadhesives. ... The area of bioadhesion in drug delivery had started some 20 years ago by using so-called mucoadhesive polymers. Many of these polymers were already used as excipients in pharmaceutical formulations. This has facilitated the development of the first bioadhesive drug ...Author: Claus-Michael Lehr
https://www.scirp.org/journal/PaperInformation.aspx?PaperID=9109
Selective targeting of drugs to the proposed site of action provides therapeutic advantages such as reduced toxicity and smaller dose levels. Despite a huge progress made in drug design and delivery systems, many challenges still have to be solved. Small therapeutic drugs always have the potential to pass into the kidneys and be excreted from the body.Author: Marija Gavrovic-Jankulovic, Radivoje Prodanovic
https://www.sciencedirect.com/science/article/pii/S0223523419307469
The drug delivery system modified by mannose can enter cells through the phagocytosis and internalization of macrophages . Therefore, the drug delivery system modified by mannose can give its liver, lung and other organs targeted. 2.1.3. Lectin-like receptorAuthor: Fang Chen, Gangliang Huang
https://www.nibib.nih.gov/science-education/science-topics/drug-delivery-systems-getting-drugs-their-targets-controlled-manner
Drug delivery systems are engineered technologies for the targeted delivery and/or controlled release of therapeutic agents. Drugs have long been used to improve health and extend lives. The practice of drug delivery has changed dramatically in the past few decades and even greater changes are …
https://www.hindawi.com/journals/ecam/2017/1594074/
Lectin-mediated bioadhesion has been an interesting characteristic for development of drug delivery systems. Lectin histochemistry and lectin-based biosensors are useful to detect transformed tissues and biomarkers related to disease occurrence; antitumor lectins reported are promising for cancer therapy.Author: Luana Cassandra Breitenbach Barroso Coelho, Priscila Marcelino dos Santos Silva, Vera Lúcia de Menez...
https://www.researchgate.net/publication/8075906_Lectin-mediated_drug_delivery_in_the_oral_cavity
Lectin-mediated drug delivery in the oral cavity. ... Lectin-containing delivery systems are a potential innovation for targeted and prolonged therapy within the oral cavity, but considerations ...Author: John D Smart
https://www.researchgate.net/publication/12616924_Lectin-mediated_drug_delivery_the_second_generation_of_bioadhesives
Lectin-mediated bioadhesion has been an interesting characteristic for development of drug delivery systems. Lectin histochemistry and lectin-based biosensors are useful to detect transformed ...
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