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https://www.sciencedirect.com/science/article/pii/S0169409X0300231X
4.3. Lectins for drug delivery within the oral cavity. The use of lectins for drug delivery within the oral cavity is still an undeveloped area. To confer a therapeutic advantage, lectin-containing delivery systems would have to: • bind rapidly and be retained for extended periods and/or; • locate and target a specific location; •Author: John D. Smart
https://www.sciencedirect.com/science/article/pii/S0141813020304840
In contrast, reverse lectin targeting employs drug-carriers conjugated with lectins that recognize specific glycans attached to the cell surface . As H-type lectins bind to glycans present at the surface of the cancer cells, these lectins can be utilized in designing drug delivery systems based on reverse lectin …Author: Agnieszka J. Pietrzyk-Brzezinska, Anna Bujacz
https://www.tandfonline.com/doi/abs/10.1080/1061186021000038300
Oct 20, 2008 · Lectin-mediated drug delivery may become a promising strategy to improve the efficacy of poorly permeable drugs by utilising active high-capacity transport pathways of epithelial tissues. This requires the elucidation of the basic mechanisms of lectin uptake prior to their practical use.Author: M. Wirth, C. Kneuer, C.M. Lehr, F. Gabor
https://www.researchgate.net/publication/12355326_Endogenous_lectins_as_targets_for_drug_delivery
On the other hand, antigen-antibody interactions typically exhibit K D in the subnanomolar range [30]. Lectins as biorecognition elements and valuable glycan affinity reagents have been broadly utilized in numerous applications, such cancer diagnostics [18,25,31], drug delivery [32],...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3027850/
The concept of lectin-mediated specific drug delivery was proposed by Woodley and Naisbett in 1988 (Bies et al., 2004).Author: Haike Ghazarian, Brian Idoni, Steven B. Oppenheimer
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3322271/
May 01, 2012 · It is possible that lectin interaction with Peyer’s patches also leads to enhanced uptake, because one potential drawback of lectin-based targeting for drug delivery applications is the potential for immunostimulatory effects .Author: Laura M. Ensign, Laura M. Ensign, Richard Cone, Richard Cone, Justin Hanes
https://health.usnews.com/wellness/food/articles/2017-11-29/the-trouble-with-lectins
Nov 29, 2017 · If you are basically healthy and don’t have digestion woes or allergy problems but wonder if you might be sensitive to certain lectins, you could try a short-term elimination diet: Cut out legumes, beans, grains and nightshades such as eggplant, tomatoes and potatoes for four weeks, Kirkpatrick explains,...Author: Stacey Colino
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