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https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4128794/
Aug 01, 2014 · The application of EDTA in drug delivery systems: doxorubicin liposomes loaded via NH 4 EDTA gradient. ... EDTA was used in a drug delivery system by adopting an NH 4 EDTA gradient method to load doxorubicin into liposomes with the goal of increasing therapeutic effects and decreasing ... NH 4 EDTA, liposome, doxorubicin, ion gradient ...Author: Yanzhi Song, Zhenjun Huang, Yang Song, Qingjing Tian, Xinrong Liu, Zhennan She, Jiao Jiao, Eliza Lu,...
https://www.quicksilverscientific.com/blog/edta-and-metal-chelation-can-a-liposomal-format-really-deliver/
EDTA and Metal Chelation: Can a Liposomal Format Really Deliver? Chelation therapy, that is, the removal of toxic metals from the body with an agent known as a chelator, is an important mainstay in toxicology and environmental medicine, both fields which deal with the impact of toxic heavy metals on the human body.
https://www.quicksilverscientific.com/quicksilver-delivery-systems/
The Quicksilver Delivery Systems® signature trademark on our liposomal products sets them apart from other companies and ensures a superior product. By virtue of our smaller, more stable, single-layer spheres, made from high-quality ingredients available, our delivery systems improve upon basic liposomal technology.
https://www.researchgate.net/publication/264793527_The_application_of_EDTA_in_drug_delivery_systems_Doxorubicin_liposomes_loaded_via_NH4EDTA_gradient
The application of EDTA in drug delivery systems: Doxorubicin liposomes loaded via NH4EDTA gradient ... EDTA was used in a drug delivery system by adopting an NH4EDTA gradient method to load ...
https://www.ncbi.nlm.nih.gov/pubmed/25120359
Aug 01, 2014 · In this study, EDTA was used in a drug delivery system by adopting an NH4EDTA gradient method to load doxorubicin into liposomes with the goal of increasing therapeutic effects and decreasing drug-related cytotoxicity. The particle size of the optimum NH4EDTA gradient liposomes was 79.4±1.87 nm, and the entrapment efficiency was 95.54%±0.59% ...Author: Yanzhi Song, Zhenjun Huang, Yang Song, Qingjing Tian, Xinrong Liu, Zhennan She, Jiao Jiao, Eliza Lu,...
https://www.omicsonline.org/open-access/liposomes-for-drug-delivery-2155-952X276-97370.html
Liposome of pure lipid’s transition temperature is 41.4°C, whereas lipids from natural origin such as lecithin exhibit broad transition temperature The upper limit of temperature for liposome formation is the Krafft point of lecithin, at 58°C and therefore temperature range between 41.4°C and 58°C is ideal for liposome formation eg ...Author: Durgavati Yadav, Kumar Sandeep, Deepak Pandey, Ranu Kumari Dutta
https://www.sciencedirect.com/science/article/pii/S0168365911001088
The effect of CCR5-conjugated liposomes containing EDTA on the viability of Namalwa cells was also compared to the cytotoxic effect exerted by synthetic EDTA-containing liposomes that serve as a control for the liposomal delivery system. CCR5-conjugated cell-derived liposomes without EDTA led to almost 30% reductions in the viability of Namalwa ...Author: Tomer Bronshtein, Naama Toledano, Dganit Danino, Shimon Pollack, Marcelle Machluf
https://en.wikipedia.org/wiki/Liposome
A liposome is a spherical vesicle having at least one lipid bilayer.The liposome can be used as a vehicle for administration of nutrients and pharmaceutical drugs. Liposomes can be prepared by disrupting biological membranes (such as by sonication).. Liposomes are most often composed of phospholipids, especially phosphatidylcholine, but may also include other lipids, such as egg ...
https://link.springer.com/referenceworkentry/10.1007/978-3-662-49231-4_6-2
Nov 05, 2018 · Furthermore, because of the chelation of EDTA, it can also reduce drug-related toxicity and liposome-related immune organ damage. In this section, the weakly amphiphilic base drugs doxorubicin, topotecan, epirubicin, and idarubicin were used as model drugs to introduce the EDTA gradient drug-loading method.
https://www.sciencedirect.com/science/article/pii/0022175996000567
ELSEVIER Journal of Immunological Methods 193 (1996) 93-99 JOURNAL OF IMMUNOLOGICAL METHODS Apoptosis of macrophages induced by liposome-mediated intracellular delivery of clodronate and propamidine Nico van Rooijen , Annemarie Sanders, Timo K. van den Berg Department of Cell Biology and Immunology.Author: N. Van Rooijen, A. Sanders, T. K. Van Den Berg
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