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https://www.sciencedirect.com/science/article/pii/S0378517306010623
The exact benefits remain unclear, as a result of paucity of reported investigations; however, it appears that combining iontophoresis with lipid vesicles facilitates drug delivery to deeper layers of skin including enhanced transfollicular delivery.Author: Mustafa M.A. Elsayed, Ossama Y. Abdallah, Viviane F. Naggar, Nawal M. Khalafallah
https://www.ncbi.nlm.nih.gov/pubmed/17222523
Mar 06, 2007 · Despite this long history of intensive research, lipid vesicles are still considered as a controversial class of dermal and transdermal carriers. Accordingly, this article provides an overview of the development of lipid vesicles for skin delivery of drugs, with special emphasis on recent advances in this field, including the development of deformable liposomes and ethosomes.Author: Mustafa M.A. Elsayed, Ossama Y. Abdallah, Viviane F. Naggar, Nawal M. Khalafallah
https://onlinelibrary.wiley.com/doi/abs/10.1211/jpp.59.10.0017
The new lipid vesicles were developed and investigated as carriers for skin delivery of the model drug, cinchocaine base. PG‐liposomes showed high entrapment efficiency and were stable for at least one month of storage at 5 ± 1 °C.Author: Mustafa M. A. Elsayed, Ossama Y. Abdallah, Viviane F. Naggar, Nawal M. Khalafallah
https://www.researchgate.net/publication/6578767_Lipid_vesicles_for_skin_delivery_of_drugs_Reviewing_three_decades_of_research
further investigation and dev elopment of lipid vesicles as carriers for skin delivery of drugs. Despite this long history of intensiv e research, lipid vesicles are still considered as a...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4352220/
Conclusion: Optimal drug entrapment in vesicles or alteration of the skin structure may not necessarily enhance the permeation of hydrophilic drugs across the human skin. These lipid vesicles may be further developed into carriers of both hydrophilic and hydrophobic drugs for topical and transdermal delivery, respectively.Author: Anahita Fathi-Azarbayjani, Kai Xin Ng, Yew Weng Chan, Sui Yung Chan
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4588690/
Sep 30, 2015 · Although the therapeutic advantages of lipid-based vesicles for skin delivery of drugs and bioactive agents have been supported by a multitude of in vitro and preclinical studies, the development of these products through the R&D pipeline has not progressed at the same pace.Author: Susan Hua
https://www.hindawi.com/journals/ap/2014/574673/
Lipid Based Vesicular Drug Delivery System Vesicular drug delivery system can be defined as highly ordered assemblies consisting of one or more concentric bilayers formed as a result of self-assembling of amphiphilic building blocks in presence of water.Author: Shikha Jain, Vikas Jain, S. C. Mahajan
https://www.researchgate.net/publication/286562597_Lipid_vesicles_for_transdermal_drug_delivery
One major problem in (trans)dermal drug delivery is the low penetration rate of drugs through the barrier of the skin. Encapsulation of a drug in lipid vesicles is one strategy to increase the ...
https://www.sciencedirect.com/science/article/pii/S0169409X03002448
The first therapeutic using lipid vesicles on the skin was commercialised shortly before the year 1990, and contained an anti-mycotic agent, econazole. A few other, relatively simple, liposome-based dermal products followed . The first marketed through the skin (=TTS) therapeutic was introduced less than a decade earlier, in 1980, and contained the drug scopolamine.Author: Gregor Cevc
https://www.sciencedirect.com/science/article/pii/S0378517317310268
Lipid nanocarriers enable to target the therapeutic payload to deep skin layers or even to reach the blood circulation making them a promising cutting-edge technology. Lipid nanocarriers refer to a large panel of drug delivery systems. Lipid vesicles are the most conventional, known to be able to carry lipophilic and hydrophilic active agents.Author: M. Sala, R. Diab, A. Elaissari, H. Fessi
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