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https://www.sciencedirect.com/science/article/pii/S2211383513000919
The availability of novel lipid excipients with acceptable regulatory and safety profiles coupled with their ability to enhance oral bioavailability has helped in the development of lipid based formulations as a means for drug delivery. Lipid-based drug delivery (LBDD) systems have gained much importance in the recent years due to their ability ...Author: Sandeep Kalepu, Mohanvarma Manthina, Veerabhadhraswamy Padavala
https://www.hindawi.com/journals/jphar/2014/801820/
The principle objective of formulation of lipid-based drugs is to enhance their bioavailability. The use of lipids in drug delivery is no more a new trend now but is still the promising concept. Lipid-based drug delivery systems (LBDDS) are one of the emerging technologies designed to address challenges like the solubility and bioavailability of poorly water-soluble drugs. Lipid-based ...Author: Kent Jørgensen, Jesper Davidsen, Charlotte Vermehren, Sven Frøkjær, Ole G. Mouritsen
https://drug-dev.com/lipid-based-delivery-are-lipid-based-drug-delivery-systems-in-your-formulation-toolbox/
Lipid-based drug delivery systems (LBDDS) is a wide-ranging designation for formulations containing a dissolved or suspended drug in lipidic excipients. Lipids are esters of fatty acids – lipophilic hydrocarbon chains linked to a hydrophilic group like glycerol, polyglycerol, or polyalcohol (Figure 1). ...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4590796/
May 19, 2014 · 2. General Routes of LBDDS. Routes like oral, parenteral, ocular, intranasal, dermal/transdermal, and vaginal can be for the administration of the lipid-based drug delivery systems (LBDDS) [4, 5].However, oral route is the most preferred route because of the properties like noninvasiveness, less expensive, and less prone to side effects, such as injection-site reactions.Author: Kent Jørgensen, Jesper Davidsen, Charlotte Vermehren, Sven Frøkjær, Ole G. Mouritsen
https://www.sciencedirect.com/topics/pharmacology-toxicology-and-pharmaceutical-science/lipid-based-drug-delivery-system
Lipid-based drug delivery systems showed great potential in overcoming problems of low bioavailability of poorly soluble drugs. Since mechanisms responsible for improving drug bioavailability are quite different from other delivery systems, these systems require application of specific characterization methods, which can simulate what happens ...
https://www.researchgate.net/publication/275064687_Lipid-Based_Drug_Delivery_Systems
The principle objective of formulation of lipid-based drugs is to enhance their bioavailability. The use of lipids in drug delivery is no more a new trend now but is still the promising concept.
https://www.intechopen.com/books/recent-advances-in-novel-drug-carrier-systems/lipid-nanoparticulate-drug-delivery-systems-a-revolution-in-dosage-form-design-and-development
Nanoparticulate drug delivery systems (DDS) have attracted a lot of attention because of their size-dependent properties. Among the array of nanoparticles being currently investigated by pharmaceutical scientists, lipid nanoparticles have taken the lead because of obvious advantages of higher degree of biocompatibility and versatility.Author: Anthony A. Attama, Mumuni A. Momoh, Philip F. Builders
http://www.americanpharmaceuticalreview.com/Featured-Articles/341191-Why-Consider-a-Lipid-Based-Drug-Delivery-System-LBDDS/
Aug 15, 2017 · Approximately 90 percent of molecules in the discovery pipeline, and approximately 40 percent of drugs with market approval, are poorly water soluble. 2 Advanced delivery technologies, like lipid-based systems, are an alternative solution to safely and effectively deliver the proper therapeutic dose to patients. Unlike conventional tablets or powder-filled capsules, LBDDS can present the drug ...Author: John Lipari
http://pharmrev.aspetjournals.org/content/pharmrev/68/3/701.full.pdf
Lipid-Based Drug Delivery Systems in Cancer Therapy: What Is Available and What Is Yet to Come Phatsapong Yingchoncharoen, Danuta S. Kalinowski, and Des R. Richardson Molecular Pharmacology and Pathology Program, Department of Pathology, Faculty of Medicine, Bosch Institute, The University of Sydney, Sydney, NSW, AustraliaAuthor: Phatsapong Yingchoncharoen, Danuta S. Kalinowski, Des R. Richardson
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