Lipid Nanoparticles For The Delivery Of Poorly Water-Soluble Drugs

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Lipid nanoparticles for the Delivery of Poorly Water ...

    https://www.researchgate.net/publication/47642868_Lipid_nanoparticles_for_the_Delivery_of_Poorly_Water-Soluble_Drugs
    This review discusses important aspects of lipid nanoparticles such as colloidal lipid emulsions and, in particular, solid lipid nanoparticles as carrier systems for poorly water-soluble drugs ...Author: Heike Bunjes

Lipid nanoparticles for the delivery of poorly water ...

    https://onlinelibrary.wiley.com/doi/full/10.1111/j.2042-7158.2010.01024.x
    Jul 20, 2010 · Different aspects have to be considered when developing lipid emulsions (and lipid nanoparticles in general) for the delivery of poorly water‐soluble drugs. Of great importance is the fact that poorly water‐soluble drugs do not necessarily display a high solubility in lipids.Author: Heike Bunjes

Solid Lipid Nanoparticles for Drug Delivery - Drug ...

    https://onlinelibrary.wiley.com/doi/10.1002/9781118444726.ch4
    The chapter on solid lipid nanoparticles introduces colloidal suspensions of crystalline lipids as carrier systems for poorly water‐soluble drugs. It describes and compares the various methods to prepare these carrier systems, in particular, different melt‐dispersion and precipitation techniques.Author: Sonja Joseph, Heike Bunjes

(PDF) Solid Lipid Nanoparticles for Poorly Water-Soluble Drugs

    https://www.researchgate.net/publication/306224119_Solid_Lipid_Nanoparticles_for_Poorly_Water-Soluble_Drugs
    Solid lipid nanoparticles (SLN) are a colloidal carrier system for the controlled delivery of drugs. To study the potential of SLN to achieve prolonged drug release prednisolone was chosen as a ...

Solid lipid nanoparticles for the controlled delivery of ...

    https://www.sciencedirect.com/science/article/abs/pii/S1350417717303723
    Solid lipid nanoparticles for the controlled delivery of poorly water soluble non-steroidal anti-inflammatory drugs. Author links open overlay panel Raj Kumar 1 Ashutosh …Author: Raj Kumar, Ashutosh Singh, Neha Garg, Prem Felix Siril

Nanocarrier for Poorly Water-Soluble Anticancer Drugs ...

    https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4113620/
    Apr 02, 2014 · A similar problem is observed with the new small-molecule anticancer drugs. Since the 1990s, the newer drug pipeline tends to have lower solubility resulting in an increase in poorly water-soluble BCS Class 2 compounds from ~30 to 50–60% and the corresponding decrease in water-soluble BCS Class 1 compounds from ~40 to 10–20% . The aqueous ...Author: Mayuri Narvekar, Hui Yi Xue, June Young Eoh, Ho Lun Wong

Lipid-based liquid crystalline nanoparticles as oral drug ...

    https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3414211/
    Lipid-based liquid crystalline nanoparticles (LCNPs) have attracted growing interest as novel drug-delivery systems for improving the bioavailability of both hydrophilic and hydrophobic drugs. However, their cellular interaction and in vivo behavior have not been fully developed and characterized.Author: Ni Zeng, Xiaoling Gao, Quanyin Hu, Qingxiang Song, Huimin Xia, Zhongyang Liu, Guangzhi Gu, Mengyin J...

Solid lipid nanoparticles (SLN): prediction of toxicity ...

    https://www.sciencedirect.com/science/article/pii/B9780128177785000014
    Various controlled drug delivery systems like polymer-based controlled-release systems, hydrogels, as well as nano- and microparticles have been introduced in recent years in order to improve solubility, stability and bioavailability of poorly water-soluble drugs. In this context, lipid nanoparticles offer attractive and ideal properties for ...Author: J.R. Campos, P. Severino, A. Santini, A.M. Silva, Ranjita Shegokar, S.B. Souto, E.B. Souto, E.B. Sou...

Drug Delivery Strategies for Poorly Water-Soluble Drugs ...

    https://www.wiley.com/en-us/Drug+Delivery+Strategies+for+Poorly+Water+Soluble+Drugs-p-9781118444672
    Drug Delivery Strategies for Poorly Water-Soluble Drugs is an essential multidisciplinary guide to this important area of drug formulation for researchers in industry and academia working in drug delivery, polymers and biomaterials. ... 4 Solid Lipid Nanoparticles for Drug Delivery 103 Sonja Joseph and Heike Bunjes. 4.1 Introduction 103.

Nanoparticle Technology for the Delivery of Poorly Water ...

    http://www.pharmtech.com/nanoparticle-technology-delivery-poorly-water-soluble-drugs
    Feb 02, 2006 · In the recent years, nanoparticle technology has emerged as a strategy to tackle such formulation problems associated with poorly water-soluble and poorly water- and lipid-soluble drugs (2, 11–13). Nanoparticles are solid colloidal particles ranging in size from 1 to 1000 nm that are used as drug delivery agents (14).

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