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https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3787071/
Jun 15, 2010 · Non-toxic lipid-coated nano-calcium-phosphate particles exhibiting high DNA transfection efficiency were prepared by a new and simple method. Efficient delivery of plasmid DNA was achieved in a mammalian cell culture using LNCP/pDNA complexes. By incorporating a calcium-phosphate core, the LNCP was able to deliver DNA very efficiently.Author: Chenguang Zhou, Bo Yu, Xiaojuan Yang, Tianyao Huo, L. James Lee, Rolf F. Barth, Robert J. Lee
https://www.researchgate.net/publication/41848207_Lipid-coated_nano-calcium-phosphate_LNCP_for_gene_delivery
Lipid-coated nano-calcium-phosphate (LNCP) for gene delivery. While calcium-phosphate has been used to deliver plasmid DNA (pDNA) for decades, the method is typically characterized by low and irreproducible transfection efficiency relative to the other non-viral approaches, such as liposomes and polymers.
https://www.deepdyve.com/lp/elsevier/lipid-coated-nano-calcium-phosphate-lncp-for-gene-delivery-UkF6GnGs1C
Jun 15, 2010 · Lipid-coated nano-calcium-phosphate (LNCP) for gene delivery. 2010-06-15 00:00:00 While calcium-phosphate has been used to deliver plasmid DNA (pDNA) for decades, the method is typically characterized by low and irreproducible transfection efficiency relative to the other non-viral approaches, such as liposomes and polymers.
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4869335/
Sep 07, 2015 · Lipid coated calcium phosphate (LCP) nanoparticles (NPs) remain an attractive option for siRNA systemic delivery. Previous research has shown that the stoichiometry of reactants affects the size and morphology of nanostructured calcium phosphate (CaP) particles.Author: Jie Tang, Li Li, Christopher B. Howard, Stephen M. Mahler, Leaf Huang, Zhi Ping Xu
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3915088/
Jan 15, 2014 · Zhou et al. have developed a novel gene transfer vector comprising lipid-coated nano-calcium-phosphate (LNCP) that provides consistently efficient and satisfactory pDNA delivery 268. It is based on core-shell nanoparticles comprising of a calcium-phosphate core and a cationic lipid shell.Author: Lian Jin, Xin Zeng, Ming Liu, Yan Deng, Nongyue He
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3588097/
Feb 21, 2013 · An example of a case where usage of lipids led to an increase in molecular passage through the plasma membrane is DNA delivery by lipid-coated nano-calcium-phosphate (LNCP).
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