We have collected information about Ligand Targeted Delivery Of Therapeutic Sirna for you. Follow the links to find out details on Ligand Targeted Delivery Of Therapeutic Sirna.
https://www.researchgate.net/publication/6936172_Ligand-Targeted_Delivery_of_Therapeutic_siRNA
Ligand-Targeted Delivery of Therapeutic siRNA. ... or have considerable potential for the targeted delivery of siRNA. The use of such ligands improves the efficiency, specificity and, as a ...
https://link.springer.com/article/10.1007%2Fs11095-006-9001-x
Jul 19, 2006 · Recent chemical modifications of siRNA have overcome problems associated with the instability of siRNA, and various ligands, including glycosylated molecules, peptides, proteins, antibodies and engineered antibody fragments, appear to be very useful or have considerable potential for the targeted delivery of siRNA.Author: Yutaka Ikeda, Kazunari Taira, Kazunari Taira
https://www.sciencedirect.com/science/article/pii/B9780123942951000044
Targeted siRNA Delivery. Targeted siRNA delivery systems for cancer are a promising new class of experimental therapeutics with the potential to revolutionize medicine with their increased efficiency and relatively low toxicity compared to conventional drugs.Author: Maneesh Gujrati, Zheng-Rong Lu
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC528817/
Nov 01, 2004 · Cancer siRNA therapy by tumor selective delivery with ligand-targeted sterically stabilized nanoparticle. ... Since RPP-nanoplexes can be used for tumor-targeted delivery of siRNA as well as plasmid DNA, the experiment was carried out in two different ways, co-delivery of plasmid with siRNA or sequential delivery of plasmid followed by siRNA 2 ...Author: Raymond M. Schiffelers, Aslam Ansari, Jun Xu, Qin Zhou, Qingquan Tang, Gert Storm, Grietje Molema, P...
https://www.hindawi.com/journals/jdd/2017/6971297/
In addition, the efficacy (or lack thereof) of the siRNA-NP may interfere with the independent evaluation of ligand-directed therapies. It is our goal in this review not only to cover the array of ligand-targeted siRNA NPs, but also to indicate possible flaws in the particular study and alert the reader to the potential of the ligand, independent of the efficacy of the NP.Author: Qixin Leng, Martin C. Woodle, A. James Mixson
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1559924/
Jun 25, 2006 · Therapeutic application of siRNA requires delivery to the correct intracellular location, to interact with the RNAi machinery within the target cell, within the target tissue responsible for the pathology. Each of these levels of targeting poses a significant ...Author: Sabrina Oliveira, Gert Storm, Raymond M. Schiffelers
https://academic.oup.com/nar/article/32/19/e149/1244527
Since RPP-nanoplexes can be used for tumor-targeted delivery of siRNA as well as plasmid DNA, the experiment was carried out in two different ways, co-delivery of plasmid with siRNA or sequential delivery of plasmid followed by siRNA 2 h later, all using RPP-nanoplex.Author: Raymond M. Schiffelers, Aslam Ansari, Jun Xu, Qin Zhou, Qingquan Tang, Gert Storm, Grietje Molema, P...
https://www.sciencedirect.com/science/article/pii/S0927776520301211
Nowadays, nanoparticle-mediated targeted drug delivery system (NTDDS) is widely used in osteosarcoma. The NTDDS includes a therapeutic agent, a delivery vehicle and a surface ligand that mediates cell internalization into tumor cells [10,11].Author: Xin Huang, Wei Wu, Wenbo Yang, Xiangcheng Qing, Zengwu Shao
https://www.nature.com/articles/nrd4519
Feb 20, 2015 · To minimize these toxicities, strategies have been developed wherein the therapeutic agent is targeted to tumour cells through conjugation to a …Author: Madduri Srinivasarao, Chris V. Galliford, Philip S. Low
https://www.cell.com/molecular-therapy-family/molecular-therapy/pdf/S1525-0016(16)31081-4.pdf
sible for the specific and potent delivery of siRNA to hepatocytes by iLNPs. The establishment of ligand-based targeting as being responsible for the potent liver delivery observed with iLNPs opens up two possibilities. First, it may be possible to use exogenously targeted iLNPs to deliver siRNA to liver through a potentially more favorable ...
Searching for Ligand Targeted Delivery Of Therapeutic Sirna?
You can just click the links above. The data is collected for you.
