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https://www.slideshare.net/shreeraj9183/iontophoresis-drug-delivery-system
Aug 28, 2012 · Advantages over other delivery system Iontophoresis enlarges the range of drug candidates for transdermal administration. Fast skin recovery than parentral route. Less risk of systemic absorption than injection. Less anxiety provoking or painful than injection Increases therapeutic efficacy by bypassing hepatic “first pass” metabolism. Inter and intra subject variability is considerably reduced …
http://ijpsr.com/bft-article/iontophoresis-controlled-transdermal-drug-delivery-system/?view=fulltext
Transdermal iontophoretic drug delivery system has one of the useful techniques in achieving the controlled delivery of pharmaceuticals, especially which drug molecules are relatively small in molecular size and rather lipophilic in nature.
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3293348/
Dec 13, 2011 · The release characteristics of drug from delivery system and the composition of drug delivery system can largely affect the transdermal permeation of drug molecules [ 39 – 41 ]. Organic solvents and surface active agents can also alter the permeability of skin …
https://www.sciencedirect.com/science/article/pii/S0169409X03002424
The Vyteris iontophoretic drug delivery system is designed to provide rapid local dermal anesthesia to minimize pain for medical procedures such as insertion of IV catheters, needle sticks for blood draws and other diagnostic procedures, and dermatological surgical procedures.Author: Yogeshvar N. Kalia, Aarti Naik, James Garrison, Richard H. Guy
https://www.researchgate.net/publication/280139168_Iontophoretic_Drug_Delivery_History_and_Applications
When the transdermal drug flux is controlled by the. device instead of the skin, delivery of the drug is more reproducible leading to smaller inter and. intrasubject variations, since the drug release from the device can be controlled accurately than the. permeability of the skin (Guy et al., 1992).
http://www.authorstream.com/Presentation/shreeraj9183-1519650-iontophoresis-drug-delivery-system/
Aug 28, 2012 · Introduction Definition:- Iontophoresis can be defined as the permeation of ionized drug molecules across biological membranes under the influence of electrical current . 3 PowerPoint Presentation: HISTORICAL DEVELOPMENT :- The idea of applying electric current to increase the penetration of electrically charged drugs into surface tissues was probably originated by varatti in 1747.
https://www.rxlist.com/ionsys-drug.htm
Oct 02, 2019 · IONSYS (fentanyl iontophoretic transdermal system) is a patient-controlled iontophoretic transdermal system providing on-demand systemic delivery of fentanyl, an opioid agonist, for up to 24 hours or a maximum of 80 doses, whichever comes first.
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2852061/
Iontophoretic delivery of several systemic drugs is still under investigation. These include the analgesic, fentanyl 32, a reversible cholinesterase inhibitor, tacrine III and several formulations of insulin 33–38. The symmetrical nature of iontophoresis, where ions are driven both into and out of the body,...
https://www.slideshare.net/ShashankSoni/brain-targeted-drug-delivery
Mar 23, 2017 · IONTOPHORETIC DELIVERY Iontophoresis is the introduction of ionised molecules into tissues by means of an electric current biologically active agent is transported by means of iontophoresis and/or phonophoresis directly to the CNS using the olfactory pathway to the brain and thereby circumventing the BBB and is known as transnasal iontophoretic delivery Roy Sandipan (2012) “Strategic Drug Delivery …
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