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https://www.researchgate.net/publication/6534600_Iontophoresis-An_Approach_for_Controlled_Drug_Delivery_A_Review
Iontophoretic drug delivery is generally considered safe and noninvasive such as in transdermal and ocular iontophoresis. For example, the US Food and Drug Administration (FDA) has approved iontophoresis treatments such as transdermal fentanyl (Ionsys in 2015, Medicines Co.,...
https://www.ingentaconnect.com/contentone/ben/cdd/2007/00000004/00000001/art00001
Various parameters which affect the transdermal absorption of drugs through iontophoresis like drug concentration, polarity of drugs, pH of donor solution, presence of co-ions, ionic strength, electrode polarity etc. have also been reviewed in detail.
http://www.eurekaselect.com/openurl/content.php?genre=article&issn=1567-2018&volume=4&issue=1&spage=1
Present review also provides an insight into reverse iontophoresis. Various parameters which affect the transdermal absorption of drugs through iontophoresis like drug concentration, polarity of drugs, pH of donor solution, presence of co-ions, ionic strength, electrode polarity etc. have also been reviewed in …
http://www.eurekaselect.com/58408/article/iontophoresis-approach-controlled-drug-delivery-review
Abstract: The recent approval of lidocaine hydrochloride and epinephrine combined iontophoretic patch (Lidosite® Vysteris Inc.) for localized pain treatment by FDA has invigorated the gaining interest in iontophoretic drug delivery systems for the transdermal delivery of drugs. This technique of facilitated movement of ions across a membrane under the influence of an externally applied electric …Author: Nitin Dixit, Vikas Bali, Sanjula Baboota, Alka Ahuja, Javed Ali
https://www.semanticscholar.org/paper/Iontophoresis-an-approach-for-controlled-drug-a-Dixit-Bali/9dc42fd41af3e70c5ad4b696afa0fca2553533f5
The recent approval of lidocaine hydrochloride and epinephrine combined iontophoretic patch (Lidosite Vysteris Inc.) for localized pain treatment by FDA has invigorated the gaining interest in iontophoretic drug delivery systems for the transdermal delivery of drugs.
https://ijpsr.com/bft-article/iontophoresis-an-approach-to-drug-delivery-enhancement/?view=fulltext
Formulation and Dosing in Iontophoresis: Iontophoresis being a physical enhancement technique for transdermal drug delivery system, a very high probability states that there is a difference in amount of dose loaded in device and the actual amount penetrating the skin layers. The amount of dose loaded on the device depends upon the technology of the device whereas the amount that crosses the skin …
https://www.academia.edu/5526533/Iontophoresis_-_An_Approach_for_Controlled_Drug_Delivery_A_Review
Iontophoresis - An Approach for Controlled Drug Delivery: A Review
https://www.researchgate.net/profile/Vikas_Bali/publication/6534600_Iontophoresis-An_Approach_for_Controlled_Drug_Delivery_A_Review/links/0fcfd50874604f0259000000/Iontophoresis-An-Approach-for-Controlled-Drug-Delivery-A-Review.pdf
Iontophoresis - An Approach for Controlled Drug Delivery Current Drug Delivery, 2007, Vol. 4, No. 1 5 ing skin from different areas of human body and observed the following rank order: abdomen> forearm> instep> heel> planter, for all subjects[74].
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3293348/
Dec 13, 2011 · Iontophoresis enhances drug delivery across the skin by two principal mechanisms: electrorepulsion and electroosmosis. Electrorepulsion is the direct effect of the applied electric field on a charged permeant. The second mechanism, electroosmosis, results from the fact that the skin supports a net negative charge at physiological pH [42, 43].
https://www.alliedacademies.org/articles/iontophoresis-a-functional-approach-for-enhancement-of-transdermal-drug-delivery.pdf
Iontophoresis in combination with chemical enhancers: Although the use of iontophoresis results in much higher drug delivery if compared with conventional passive delivery, it still has limitations as a technique. Chemical enhancers can be given in combination with iontophoresis to achieve even higher drug penetration.Author: Prabhakar Satwaji Panzade
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