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https://pdfs.semanticscholar.org/7e25/fe6cd5e1967869202cf1d2a8e7264a45f974.pdf
Ion-pair drug delivery can also apply for inhalation therapy for infectious lung diseases like tuberculosis. Potent anti-tuberculosis drug, isoniazid was modified into an ionizable form suitable for hydrophobic ion pairing. The charged prodrug, sodium isoniazid methanesulfonate (Na-
https://onlinelibrary.wiley.com/doi/pdf/10.1002/9781118943182.ch12
The chapter reports the application of ion pairing and metal complexation to a number of different drug molecules sorted by administration route. The ion pairing approach can be useful to improve transdermal delivery by enhancing drug penetration through the stratum corneum.Author: Stefano Giovagnoli, Aurélie Schoubben, Carlo Rossi
https://www.researchgate.net/publication/272340513_Ion-paired_Drug_Delivery_An_Avenue_for_Bioavailability_Improvement
present the usefulness of ion-pair for improving the poor bioavailability of ionic drugs through various routes. The review covers an update on the applications of this strategy to improve drug delivery through various. routes of administration including ocular, oral, parenteral and transdermal.
https://www.ajol.info/index.php/sljbr/article/view/71806
Ion-paired Drug Delivery: An Avenue for Bioavailability Improvement Ion-pairing is reported to improve the lipophilicity and subsequently the transport rate of polar drugs across lipid membranes. Lipophilisation of ionic drugs with high aqueous solubilities by ion-pair formation with appropriate counter-ion have proven to be promising for several applications.Author: PK Suresh, SD Paul
https://www.researchgate.net/publication/339365853_HYDROPHOBIC_ION-PAIRED_DRUG_DELIVERY_SYSTEM_A_REVIEW
ion pairs which are used in the assay of drug release in pharmaceutical technology, and soluble ion pairs 21 . Based on the number of ions involved; binary ion pairs
https://www.sciencedirect.com/science/article/pii/S037851731730100X
1. Hydrophobic ion pairing of LEU with sodium docusate (■), sodium oleate (δ) and sodium dodecyl sulfate (x). After the addition of surfactants, the precipitated LEU complex was centrifuged and the remaining peptide in supernatant was analyzed by HPLC.Author: Janine Griesser, Gergely Hetényi, Michael Moser, Frédéric Demarne, Vincent Jannin, Andreas Bernkop-S...
https://www.sciencedirect.com/science/article/pii/S0378517319301760
Self-emulsifying drug delivery systems (SEDDS) are homogeneous, isotropic mixtures of oils, surfactants and co-solvents spontaneously forming oil in water emulsions after dilution with gastrointestinal (GI) fluids (Gursoy and Benita, 2004, Karamanidou et al., 2015).Author: Imran Nazir, Imran Nazir, Mulazim Hussain Asim, Mulazim Hussain Asim, Aida Dizdarević, Andreas Bernk...
https://www.ncbi.nlm.nih.gov/pubmed/28188875
Mar 30, 2017 · Hydrophobic ion pairing: Key to highly payloaded self-emulsifying peptide drug delivery systems. Griesser J(1), Hetényi G(1), Moser M(1), Demarne F(2), Jannin V(2), Bernkop-Schnürch A(3). Author information: (1)Thiomatrix Forschungs-und Beratungs GmbH Trientlgasse 65, Innsbruck, Austria.Author: Janine Griesser, Gergely Hetényi, Michael Moser, Frédéric Demarne, Vincent Jannin, Andreas Bernkop-S...
https://pubs.acs.org/doi/abs/10.1021/mp100050d
Abstract. Antiviral drugs often suffer from poor intestinal permeability, preventing their delivery via the oral route. The goal of this work was to enhance the intestinal absorption of the low-permeability antiviral agents zanamivir heptyl ester (ZHE) and guanidino oseltamivir (GO) utilizing an ion-pairing approach,...Author: Jonathan M. Miller, Arik Dahan, Deepak Gupta, Sheeba Varghese, Gordon L. Amidon
https://www.tandfonline.com/doi/abs/10.1517/17425247.2016.1123247
Jul 28, 2014 · (2016). Clarithromycin ion pair in a liposomal membrane to improve its stability and reduce its irritation caused by intravenous administration. Expert Opinion on Drug Delivery: Vol. 13, No. 3, …Author: Geng S, Liu X, Xu H, Cai C, Zhang Y, Yao Q, Gou J, Yin T, Xiao W, Tang X
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