We have collected information about Intraocular Drug Delivery for you. Follow the links to find out details on Intraocular Drug Delivery.
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2895432/
May 01, 2010 · Ocular drug delivery has been a major challenge to pharmacologists and drug delivery scientists due to its unique anatomy and physiology. Static barriers (different layers of cornea, sclera, and retina including blood aqueous and blood–retinal barriers), dynamic barriers (choroidal and conjunctival blood flow, lymphatic clearance, and tear dilution), and efflux pumps in conjunction pose a ...Author: Ripal Gaudana, Hari Krishna Ananthula, Ashwin Parenky, Ashim K. Mitra
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3306122/
Dec 26, 2010 · To overcome the above mentione d limitations, an increasing number of sustained-release drug delivery devices using different mechanisms and containing a variety of agents have been developed to treat uveitis. This article reviews major drug delivery technologies currently in clinical trials or at experimental stages for treatment of uveitis.Author: Nahid Haghjou, Masoud Soheilian, Mohammad Jafar Abdekhodaie
https://www.sciencedirect.com/science/article/pii/S0142961220302076
Dually functional hollow ceria nanoparticle platform for intraocular drug delivery: A push beyond the limits of static and dynamic ocular barriers toward glaucoma therapy. Author links open overlay panel Li-Jyuan Luo a 1 Duc Dung Nguyen a 1 Jui-Yang Lai a b c. Show more.Author: Li-Jyuan Luo, Duc Dung Nguyen, Jui-Yang Lai
https://www.aao.org/annual-meeting-video/intraocular-drug-delivery-systems
Dr. Jonathan Myers discusses sustained-release drug delivery, which has the potential to eliminate compliance problems. Additionally, intraocular delivery might reduce topical side effects and allow much lower total dosages of medication.
https://www.sciencedirect.com/topics/nursing-and-health-professions/intraocular-drug-administration
Ocular drug delivery studies in past decades have employed in vivo animal models, such as rabbits, and have been conducted in vitro by using isolated rabbit ocular tissues, which also implies the sacrifice of a huge number of animals. ... Intraocular administration of antibiotics is widely accepted as standard care in endophthalmitis.
http://www.mavery.com/academic/Intraocular_DDS.pdf
injections. This drug delivery system is currently used to treat CMV retinitis and research is being done to apply the technology to a variety of eye diseases. Is there a better intraocular drug delivery system? There is an obvious problem with the intraocular DDS described above though.
https://www.assignmentpoint.com/science/medical/intraocular-implants-for-extended-drug-delivery.html
Intraocular implants for drug delivery are capable of bypassing the barriers to intraocular drug absorption and avoid frequent procedures required using intravitreal injection therapy. Drug release rates of implants can be controlled so that therapeutic drug levels are maintained in the eye, while avoiding toxic or subtherapeutic levels.
https://pharm.ucsf.edu/desai/research/ocular-drug-delivery
One attractive platform for continuous delivery of antibody-based therapeutics is the use of nanoporous materials. We are developing injectable nanoporous devices for long-term drug delivery to the eye. Current efforts are directed toward tuning our devices for constant drug release and timely degradation.
https://journals.lww.com/co-ophthalmology/Fulltext/2013/01000/Intraocular_lens_as_a_drug_delivery_reservoir.11.aspx
Purpose of review To describe the development and use of intraocular lenses (IOLs) as drug delivery systems and to review the current literature on their application and efficacy.. Recent findings Many drugs have been loaded onto IOLs by coating or by attachment in a separate reservoir.
https://www.ondrugdelivery.com/biodegradable-implants-sustained-intraocular-delivery-small-large-molecules/
Re-Vana Therapeutics is an ocular pharmaceuticals and drug delivery company focused on the development and commercialisation of long-acting biodegradable drug delivery platforms to treat chronic eye diseases. It is a spin-out company from the School of Pharmacy, Queens University Belfast.
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