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https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3653240/
Apr 08, 2013 · Intranasal Delivery of Drug to Awake Mice Introduction Using the intranasal grip, each mouse is restrained twice and held with their neck parallel to the floor while a …Author: Leah R. Hanson, Jared M. Fine, Aleta L. Svitak, Katherine A. Faltesek
https://www.jove.com/video/4440/intranasal-administration-of-cns-therapeutics-to-awake-mice
Intranasal drug can be delivered to large groups of mice for extended periods of time with minimal effort. A single group of up to 20 mice can be intranasally treated by a single person in less than one hour. A vast array of molecules, ranging from small iron chelators to …Author: Leah R. Hanson, Jared M. Fine, Aleta L. Svitak, Katherine A. Faltesek
https://journals.physiology.org/doi/pdf/10.1152/ajplung.00173.2001
tion for the chosen volumes. Intranasal delivery is often carried out after intraperitoneal (9, 19) or inha-lation (5, 14, 15) anesthesia but has also been per-formed with fully awake mice (1, 6, 17). The position of the mouse during intranasal delivery has also varied between studies, with …
https://www.jove.com/video/58485/novel-methods-for-intranasal-administration-under-inhalation
As intranasal administration necessitates mask removal for repeated administration and sufficient time for sustained nasal cavity delivery, there is a high probability that mice would awaken from anesthesia during the administration procedure.Author: Takanori Kanazawa, Mitsuyoshi Fukuda, Naoto Suzuki, Toyofumi Suzuki
https://www.youtube.com/watch?v=ny_MVCnkLRc
Jun 30, 2016 · "The truth about mobile phone and wireless radiation" -- Dr Devra Davis - Duration: 1:01:30. The University of Melbourne Recommended for you
https://www.sciencedirect.com/science/article/pii/S0361923018303678
Models of nasal drug delivery can be used for detecting and testing nasal drug absorption and permeation, for PK/PD studies, toxicological and electrophysiological studies, and also for assessment of drug transporter interaction and the nasal barrier. Models commonly used in nasal drug delivery experiments are in vitro, in vivo and ex vivo models. The different models can be used for various …Author: Franciska Erdő, Luca Anna Bors, Dániel Farkas, Ágnes Bajza, Sveinbjörn Gizurarson
https://www.sciencedirect.com/science/article/pii/S0378517315004408
Due to the particular anatomical features of the nasal cavity, intranasal administration has been explored as a means of preferential drug delivery to the brain. The purpose of the present study was to assess the pharmacokinetics of lamotrigine administered by the intranasal route to mice, and to investigate whether a direct transport of the drug from nose to brain could be involved.Author: Ana Serralheiro, Gilberto Alves, Gilberto Alves, Ana Fortuna, Amílcar Falcão
https://www.nature.com/articles/srep41768
Jan 31, 2017 · Intranasal delivery of neuroprotective ST266 is a potential novel, noninvasive therapeutic modality for the eyes, optic nerves and brain. The unique combination of biologic molecules in ST266 ...Author: Reas S. Khan, Kimberly Dine, Bailey Bauman, Michael Lorentsen, Lisa Lin, Helayna Brown, Leah R. Hans...
https://www.celerion.com/wp-content/uploads/2015/05/Celerion_050515_TIDES_Intranasal-Drug-Delivery.pdf
Pump Delivery. Pump delivery testing should be performed to assess delivery and reproducibility. Typically, the weight of individual sprays should be within 15% or the target weight, and their mean within 10% of the target weight .File Size: 1MB
https://www.emsworld.com/article/10251608/intranasal-drug-administration-innovative-approach-traditional-care
Apr 05, 2011 · Intranasal drug administration offers all levels of EMS providers a safe and effective alternative for drug delivery Intranasal Drug Administration: An Innovative Approach to Traditional Care ...
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