Intranasal Delivery Mice

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Intranasal Administration of CNS Therapeutics to Awake Mice

    https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3653240/
    Apr 08, 2013 · The Intranasal Grip to Immobilize Awake Mice. Place the mouse on the cage top. With the thumb and index finger of your dominant hand, hold the mouse by the tail. Using your middle, ring, and pinky fingers, lightly pin the ... Using the thumb and …Author: Leah R. Hanson, Jared M. Fine, Aleta L. Svitak, Katherine A. Faltesek

Intranasal delivery bypasses the ... - PubMed Central (PMC)

    https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2604883/
    Dec 10, 2008 · Intranasal insulin improves memory, attention, and functioning in patients with Alzheimer's disease or mild cognitive impairment, and even improves memory and mood in normal adult humans. This new method of delivery can revolutionize the treatment of Alzheimer's disease, stroke, and other brain disorders.Author: Leah R Hanson, William H Frey, William H Frey

Distribution of intranasal instillations in mice: effects ...

    https://www.physiology.org/doi/full/10.1152/ajplung.00173.2001
    Intranasal delivery is often carried out after intraperitoneal (9, 19) or inhalation (5, 14, 15) anesthesia but has also been performed with fully awake mice (1, 6, 17). The position of the mouse during intranasal delivery has also varied between studies, with horizontal and head-down supine positions having been used. The specific delivery protocols used in these studies are thought to influence the …Author: D. S. Southam, M. Dolovich, P. M. O'Byrne, M. D. Inman

Nasal vaccine delivery attenuates brain pathology and ...

    https://www.nature.com/articles/s41541-020-0172-y
    Mar 24, 2020 · Nasal vaccine delivery attenuates brain pathology and cognitive impairment in tauopathy model mice Skip to main content Thank you for visiting nature.com.Author: Hiroki Takeuchi

Evaluation of intranasal delivery route of drug ...

    https://www.sciencedirect.com/science/article/pii/S0361923018303678
    Models of nasal drug delivery can be used for detecting and testing nasal drug absorption and permeation, for PK/PD studies, toxicological and electrophysiological studies, and also for assessment of drug transporter interaction and the nasal barrier. Models commonly used in nasal drug delivery experiments are in vitro, in vivo and ex vivo models. The different models can be used for various …Author: Franciska Erdő, Luca Anna Bors, Dániel Farkas, Ágnes Bajza, Sveinbjörn Gizurarson

Protocol for intranasal inoculation of mice

    https://www.uab.edu/sites/luckielab/protocols/ininnoc.doc
    Protocol for intranasal inoculation of mice Frozen culture of F. tularensis LVS was thawed and diluted in PBS so as to obtain the required concentration (CFUs) in 20 ul. Prior to inoculation, all the mice are anaesthetized with intraperitoneal injection of 100 μl cocktail of Ketamine HCl and Xylazine.

Enhanced intranasal delivery of mRNA vaccine by overcoming ...

    https://www.sciencedirect.com/science/article/pii/S0168365916301079
    Mice were anesthetized with 1% (w/v) sodium pentobarbital and given intranasal doses of CP 2 k/mRNA, PEI 25 k/mRNA or naked mRNA (10 μg mRNA/mouse). As negative controls, mice received no treatment or unrelated mRNA encoding luciferase complexed with CP 2k, which excludes effects of RNA-mediated immune stimulation.Author: Man Li, Mengnan Zhao, Yao Fu, You Li, Tao Gong, Zhirong Zhang, Xun Sun

Intranasal infection of mice - YouTube

    https://www.youtube.com/watch?v=u2F6UU0dQw0
    Jan 27, 2015 · A Wicked Harpoon Eyed Spring Loaded Mouse Trap From The Civil War Era. Mousetrap Monday - Duration: 11:08. Shawn Woods Recommended for you. New

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