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https://www.healthline.com/health/intramuscular-injection
An intramuscular injection is a technique used to deliver a medication deep into the muscles. This allows the medication to be absorbed into the bloodstream quickly. You may have received an intramuscular injection at a doctor’s office the last time you got a vaccine, like the flu shot.Author: Jacquelyn Cafasso
https://www.medicalnewstoday.com/articles/323115
Sep 19, 2018 · Intramuscular injections offer some benefits over other types of delivery methods, such as oral, intravenous injections into a vein, and subcutaneous injections into fatty tissue under the skin.
https://www.hindawi.com/journals/jir/2019/8303648/
Intradermal immunization for vaccine delivery is an upcoming strategy showing significant advantages over conventional vaccination routes. In particular, in the last few years, intradermal vaccination has gained momentum as an alternative and more effective vaccine delivery route, both from a scientific and a commercial point of view (Table 3).Author: E. Criscuolo, V. Caputo, V. Caputo, R. A. Diotti, R. A. Diotti, G. A. Sautto, G. A. Kirchenbaum, N. ...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3465129/
The invention by Moyer describes methods and systems for generating a safe and effective oral smallpox vaccine for humans using a genetically defective strain of vaccinia virus to confer immunity following oral delivery of the vaccine. The vaccine invention can be delivered as a live virus with the ability to express viral proteins but unable to achieve complete lytic virus replication, or be delivered …
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3109217/
This paper highlights in a significant non-human primate vaccine challenge model many of the key aspects of DNA vaccines that make the platform attractive for vaccine development: Formulation and delivery of 8 plasmids at high concentrations and microvolumes; DNA delivery comparing intradermal and intramuscular electroporation both of which were found to be effective in controlling viremia and …Author: Niranjan Y Sardesai, David B Weiner
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