Intracochlear Drug Delivery Systems

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Intracochlear Drug Delivery Systems - PubMed Central (PMC)

    https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3159727/
    Intracochlear drug delivery systems are emerging in response to recent advances in molecular biology and understanding of the mechanisms underlying inner ear diseases, and as a means to overcome many of the barriers and limitations of conventional drug …Author: Jeffrey T Borenstein

Intracochlear drug delivery systems.

    https://www.ncbi.nlm.nih.gov/pubmed/21615213
    AREAS COVERED: Recent progress in the development of drug delivery systems capable of direct intracochlear delivery is reviewed, including passive systems such as osmotic pumps, active microfluidic devices and systems combined with currently available devices such as cochlear implants.Author: Jeffrey T Borenstein

Intracochlear drug delivery systems: a novel approach ...

    https://www.tandfonline.com/doi/pdf/10.1080/17425247.2018.1444026
    reciprocating intracochlear delivery system has been devel-oped, in which a precision micromechanical pump is operated in a push-pull mode to mix drug into perilymph while main-taining a constant fluid volume in the inner ear [22,23]. A prototype of this system is …Author: M. Peppi, A. Marie, C. Belline, J. T. Borenstein

Intracochlear Drug Delivery Systems - ResearchGate

    https://www.researchgate.net/publication/51167783_Intracochlear_Drug_Delivery_Systems
    Intracochlear Drug Delivery Systems. Introduction: Advances in molecular biology and in the basic understanding of the mechanisms associated with sensorineural hearing loss and other diseases of the inner ear are paving the way towards new approaches for treatments for millions of patients.

Intracochlear Drug Delivery Systems - Europe PMC Article ...

    http://europepmc.org/articles/PMC3159727
    Intracochlear drug delivery systems are emerging in response to recent advances in molecular biology and understanding of the mechanisms underlying inner ear diseases, and as a means to overcome many of the barriers and limitations of conventional drug …

The role of intracochlear drug delivery devices in the ...

    https://www.ncbi.nlm.nih.gov/pubmed/25347140
    AREAS COVERED: Advances in the development of intracochlear drug delivery systems are reviewed, including passive systems, active microfluidic technologies and cochlear prosthesis-mediated delivery. This article provides a description of novel delivery systems and their potential future clinical applications in treating inner ear disease.Author: Andrew M Ayoob, Jeffrey T Borenstein

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