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https://www.sciencedirect.com/topics/medicine-and-dentistry/intraarterial-drug-administration
Intraarterial administration of thrombolytic drugs allows lower systemic and higher local levels of the drug at the site of a thrombus. An initial case series reported on intraarterial administration of urokinase in five patients with an angiographically confirmed arterial occlusion [21].
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4706947/
Intra-arterial (IA) delivery is one technique for targeting the tumor site with multiple agents. Although IA chemotherapy for glioblastoma (GBM) has been attempted since the 1950s, the predicted benefits remain unproven in clinical practice. This review focuses on innovative approaches to IA drug delivery in …Author: Jason A. Ellis, Matei Banu, Shaolie S. Hossain, Rajinder Singh-Moon, Sean D. Lavine, Jeffrey N. Bruc...
https://www.hopkinsmedicine.org/interventional_neuroradiology/conditions_procedures/progressive_diffuse_intrinsic_pontine_glioma.html
Intra-arterial chemotherapy delivers the anti-cancer medication directly to the tumor via the vertebral artery, which supplies the tumor, thereby transforming the treatment from systemic (delivered to the whole body) to local chemotherapy (delivered directly to the tumor) and limits the complications and adverse effects of chemotherapy.
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3998643/
Intra-arterial delivery with BBB disruption. Intra-arterial (IA) administration of a drug is designed to increase the concentration of a drug delivered to a vascular territory by eliminating first passage metabolism. However, for drugs that have rapid transit through the CNS, there may be limited dwell time, resulting in limited efficacy.Author: Jaishri Blakeley
https://www.researchgate.net/publication/6408151_Intra-arterial_Drug_Delivery
Request PDF Intra-arterial Drug Delivery The therapeutic potential of intra-arterial (IA) drug delivery to the brain has received limited attention in the last ...
https://www.cancercenter.com/treatment-options/chemotherapy/regional-therapies
Intraperitoneal chemotherapy provides a concentrated dose of drugs to the cancer cells in the abdominal cavity. The chemotherapy is also absorbed into the bloodstream, reaching cancer cells outside the abdomen. Higher doses of chemotherapy drugs may be administered intraperitoneally, or directly into a body cavity,...
https://www.quora.com/What-is-the-difference-between-intravenous-and-intra-arterial-route-for-the-administration-of-a-drug
Mar 23, 2018 · An intravenous injection is obviously an injection into a vein and virtually all intravascularly administered medicines are given this way. Most medicines are not appropriate for intra arterial injection and may be very dangerous to give that way.
https://medical-dictionary.thefreedictionary.com/intraarterial
intraarterial: ( in'tră-ar-tē'rē-ăl ), Within an artery or the arteries.
https://clincancerres.aacrjournals.org/content/12/8/2563
Apr 15, 2006 · Transcatheter arterial chemoembolization (TACE) involves the emulsification of chemotherapeutic agent in an oily medium, used in this case as a drug carrier, and delivered intra-arterially to liver tumors for maximum effect.Author: Kelvin Hong, Afsheen Khwaja, Eleni A Liapi, Michael S. Torbenson, Christos S Georgiades, Jean Franco...
https://www.drugs.com/condition/intra-arterial-digital-subtraction-angiography.html
31 rows · Medication List About Intra-arterial Digital Subtraction Angiography: Intra-arterial Digital …
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