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https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6015522/
Intra-articular (IA) drug delivery presents many advantages as it offers direct access to the joint space, thus increasing the bioavailability of therapeutic agents at the affected site while reducing systemic exposure, potential side effects and overall cost. ... This is a PDF file of an unedited manuscript that has been accepted for ...Author: Muhammad Farooq Rai, Christine T.N. Pham
https://www.researchgate.net/publication/23656785_Intra-Articular_Drug_Delivery_A_Fast_Growing_Approach
Intra-Articular Drug Delivery: A Fast Growing Approach Article · Literature Review (PDF Available) · February 2008 with 2,319 Reads How we measure 'reads'Author: Maha Nasr
https://www.nature.com/articles/s41584-018-0123-4
Nov 29, 2018 · Intra-articular drug delivery has a number of advantages over systemic administration; however, for the past 20 years, intra-articular treatment options for …Author: Ian A. Jones, Ryan Togashi, Melissa L. Wilson, Nathanael Heckmann, C. Thomas Vangsness
https://www.sciencedirect.com/science/article/pii/S0927776517301224
Jun 01, 2017 · Intra-articular injection is an improved treatment modality for knee OA due to its superiority in the localized drugs release. However, intra-articular injectable drugs have the disadvantage of low retention time after injection, which is because the natural biological metabolism of joint fluid eliminates drug molecules rapidly.Author: Zhiwei He, Beiyue Wang, Changmin Hu, Jianning Zhao
https://www.academia.edu/2490408/Intra-articular_drug_delivery_a_fast_growing_approach
Intra-articular drug delivery: a fast growing approach
https://www.sciencedirect.com/science/article/pii/S1471489217301431
Introduction. Intra-articular (IA) drug delivery presents many advantages as it offers direct access to the joint space, thus increasing the bioavailability of therapeutic agents at the affected site while reducing systemic exposure, potential side effects and overall cost.Author: Muhammad Farooq Rai, Christine T.N. Pham
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2702533/
This section discusses microparticles, liposomes, and other emerging drug delivery systems that promise to greatly improve intra-articular drug delivery to the TMJ. Intra-articular hyaluronic acid formulations consist of colloidal dispersions of HA in aqueous solution, which form hydrogel structures . In the United States, these agents are the ...Author: Paschalia M. Mountziaris, Phillip R. Kramer, Antonios G. Mikos
http://www.eurekaselect.com/92876/article
Title: Intra-Articular Drug Delivery: A Fast Growing Approach VOLUME: 2 ISSUE: 3 Author(s):Maha Nasr Sayed Aly Affiliation:Department of Pharmaceutics, Faculty of Pharmacy, Ain Shams University, Cairo, Egypt. Keywords:Intraarticular, hyaluronic acid, hydrogels, sustained release, osteoarthritis, rheumatoid arthritis Abstract: Joint diseases are a leading cause of pain and disability in the ...Author: Maha Nasr Sayed Aly
https://dukespace.lib.duke.edu/dspace/bitstream/handle/10161/3360/274423200009.pdf%3bsequence=1
Evaluating Intra-Articular Drug Delivery for the Treatment of Osteoarthritis in a Rat Model Kyle D. Allen, Ph.D.,1 Samuel B. Adams, Jr., M.D.,1 and Lori A. Setton, Ph.D.1,2 Osteoarthritis (OA) is a degenerative joint disease that can result in joint pain, loss of joint function, and deleterious effects on activity levels and lifestyle habits.
https://www.hindawi.com/journals/jnt/2012/748909/
Abstract. The objective of this paper is to provide readers with current developments of intra-articular drug delivery systems. In recent years, although the search for a clinically successful ideal carrier is ongoing, sustained-release systems, such as polymeric micro- and nanoparticles, liposomes, and hydrogels, are being extensively studied for intra-articular drug delivery purposes.Author: Zhiyue Zhang, Guihua Huang
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