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https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3202607/
May 01, 2010 · RNA interference (RNAi) is a powerful approach for silencing genes associated with a variety of pathologic conditions; however, in vivo RNAi delivery has remained a major challenge due to lack of safe, efficient, and sustained systemic delivery.Author: Takemi Tanaka, Takemi Tanaka, Lingegowda S. Mangala, Pablo E. Vivas-Mejia, René Nieves-Alicea, Aman ...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2698461/
RNA interference (RNAi) is caused by small (21 − 23 bases long) single-stranded RNA molecules (small-interfering RNA; siRNA), which trigger silencing of target genes in a sequence-specific manner [1,2]. The siRNA's sequence is ‘anti-sense’ (or complementary) to a specific stretch of the messenger RNA (mRNA) transcribed by the target gene.Author: Saroj P Mathupala
https://www.jove.com/video/57390/double-stranded-rna-oral-delivery-methods-to-induce-rna-interference
Double-stranded RNA (dsRNA)-mediated RNA interference (RNAi) is a gene silencing mechanism for functional genomic studies that has potential applications as a tool for the management of insect pests. Exogenously synthesized dsRNA or small interfering RNA (siRNA) can trigger highly efficient gene silencing through the degradation of endogenous RNA, which is homologous to that presented.Author: Saikat Kumar B. Ghosh, Wayne B. Hunter, Alexis L. Park, Dawn E. Gundersen-Rindal
https://www.ncbi.nlm.nih.gov/pubmed/29782023
May 04, 2018 · Double-stranded RNA (dsRNA)-mediated RNA interference (RNAi) is a gene silencing mechanism for functional genomic studies that has potential applications as a tool for the management of insect pests. Exogenously synthesized dsRNA or small interfering RNA (siRNA) can trigger highly efficient gene silencing through the degradation of endogenous RNA, which is homologous to that …Author: Saikat Kumar B. Ghosh, Wayne B. Hunter, Alexis L. Park, Dawn E. Gundersen-Rindal
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