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https://www.alzforum.org/therapeutics/nasal-insulin
A subsequent four-month study then compared 20 IUs twice daily of insulin detemir to 20 IUs of regular insulin twice daily in 90 patients. Both trials looked for effects on a memory composite and six different secondary outcomes; results are not yet published. For more trials on nasal insulin in …
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4787057/
NASAL INSULIN. In theory, intranasal delivery has several advantages over oral (bypass GI peptidases), subcutaneous (noninvasive and painless) and inhalation route (no issue with lung function) which makes this route attractive for the delivery of insulin.
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3539067/
Oct 18, 2012 · The ViaNase device has been used to deliver nasal insulin in patients with early Alzheimer’s disease (AD), and clinical benefit has been demonstrated [74, 75]. In these studies, delivery of insulin was performed over a 2-min period by nasal inhalation.Author: Per Gisle Djupesland
https://www.lostfalco.com/intranasal-insulin/
This prevents nasal insulin from entering the bloodstream and makes it extremely safe (although there is always risk no matter what substance you are taking) since intranasal delivery directs the insulin into the brain, avoiding systemic side-effects. R
https://www.webmd.com/diabetes/inhaled-insulin
Inhaled insulin is another option for people with diabetes to control their blood sugar. It works for both type 1 and type 2 diabetes, but you shouldn't use it if you smoke or have asthma or COPD.
https://www.sciencedirect.com/science/article/pii/S0169409X98000738
Intranasal insulin delivery has been widely investigated as an alternative to subcutaneous injection for the treatment of diabetes. The pharmacokinetic profile of intranasal insulin is similar to that obtained by intravenous injection and, in contrast to subcutaneous insulin delivery, bears close resemblance to the `pulsatile' pattern of endogenous insulin secretion during meal-times.Author: Michael Hinchcliffe, Lisbeth Illum
https://www.diabetesdaily.com/learn-about-diabetes/treatment/other-drugs/baqsimi-glucagon-delivered-as-a-nasal-powder/
Glucagon is a hormone naturally produced by the alpha cells of the pancreas. Its activity opposes that of insulin, and it can rapidly raise blood glucose levels.Glucagon stimulates the release of glycogen (branched glucose molecules) from the liver, thereby raising …
https://www.diabeticsweekly.com/is-intranasal-insulin-therapy-safe/
In this case, insulin is administered. Therapy is integral for people with Type 1 diabetes. And, for some people with diabetes with Type 2 diabetes, too. In most cases, insulin is injected into the body. Injection pens, pumps, and patches are some of the ways …
https://www.nia.nih.gov/alzheimers/clinical-trials/study-nasal-insulin-fight-forgetfulness-sniff
26 rows · In this study, 240-300 people with amnestic MCI or mild Alzheimer's will be given either …
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