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https://www.ncbi.nlm.nih.gov/pubmed/29779482
Nanocrystals technology is an attractive method for water-insoluble drug transdermal delivery, as the literature demonstrated that the penetration and bioavailability of the transdermal delivered water-insoluble drugs significantly enhanced and improved by the nanocrystals technology.Author: Yangyang Liu, Juan Zhao, Lulu Wang, Beibei Yan, Yu Gu, Ping Chang, Yancai Wang
https://www.self.com/story/soluble-vs-insoluble-fiber
May 15, 2019 · The flesh of the apple contains some soluble fiber, while the skin is full of insoluble fiber, Whitney Linsenmeyer, Ph.D., R.D., instructor in the department of nutrition and dietetics at Saint ...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4374630/
This study demonstrates for the first time the ability to coat solid dispersions on microneedles as a means to deliver water-insoluble drugs through the skin. Polyethylene glycol (PEG) was selected as the hydrophilic matrix, and lidocaine base was selected as the …Author: Yunzhe Ma, Harvinder S. Gill
https://www.nature.com/articles/srep26278
May 18, 2016 · Skin, being the largest organ of the body, is an important site for drug administration. However, most of the drugs have poor permeability and thus …Author: Ankur Gautam, Jagpreet Singh Nanda, Jesse S. Samuel, Manisha Kumari, Priyanka Priyanka, Gursimran Be...
https://www.cosmeticsandtoiletries.com/research/chemistry/Topical-Delivery-of-Skin-Care-Ingredients--275454911premium.html
Sep 17, 2014 · Incorporating performance ingredients in a formula does not guarantee they will penetrate the skin and deliver the claimed benefits. This review presents topical delivery approaches introduced in the past five years to improve the efficacy of benefit ingredients for skin care. Examples include molecular, carrier and Trojan horse delivery. Non-conventional delivery systems also are described.
https://www.thefreelibrary.com/Skin+Care+Delivery+Systems.-a072609462
Mar 01, 2001 · Skin care delivery systems: take a closer look at the latest trends and new ideas in skin treatment. What's new in cosmetic R&D: high performance products call for innovative formulating techniques and novel materials too. Novel active cosmetic ingredient: do those anti-aging cosmetics in your medicine cabinet do more than beautify the skin?
http://www.freepatentsonline.com/4645502.html
Feb 24, 1987 · A medical device for the transdermal delivery of highly ionized, fat insoluble drugs comprises an aqueous drug reservoir having a physiological pH, said reservoir preferably being a gel maintained in an impermeable receptacle by a highly permeable support member disposed between the gel and a permeable contact adhesive.
https://pharmaceutical.basf.com/global/en/drug-formulation/solution-platforms/skin-delivery.html
An understanding of excipient behavior both in providing a stable formulation and supporting topical drug delivery is the first element of effective skin-delivery formulation design. In this video, Dr. Amy Ethier demonstrates how the BASF Pharma Solutions lab in Tarrytown, NY, can be a robust resource in your skin-delivery formulation efforts.
https://www.sciencedirect.com/science/article/pii/S0168365911005815
Efficient skin permeation of soluble proteins via flexible and functional nano-carrier. ... can act as an efficient delivery vehicle of hydrophilic proteins across human skin. The functional nano-carrier (< 100 nm in size), chemically-crosslinking Pluronic F 127 with chitosan conjugation, is flexible and soft with reservoir characteristics for ...Author: Won Il Choi, Jong Hyun Lee, Ja-Young Kim, Jin-Chul Kim, Young Ha Kim, Giyoong Tae
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