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https://www.sciencedirect.com/science/article/pii/S0753332206002587
Innovative nanotechnologies for the delivery of oligonucleotides and siRNA. ... Interference strategy and siRNA delivery. A novel, ... nuclease resistance, thermal stability and pharmacokinetic properties can be incorporated in active siRNA oligonucleotides. Modifications can be made throughout the duplex, ...Author: N. Toub, N. Toub, C. Malvy, E. Fattal, P. Couvreur
https://www.sciencedirect.com/science/article/abs/pii/S0753332206002587
Innovative nanotechnologies for the delivery of oligonucleotides and siRNA. Author links open overlay panel N. Toub a b C. Malvy b E. Fattal a P. Couvreur a. ... This review focuses on the recent developments in the design of nanotechnologies to improve the delivery …Author: N. Toub, N. Toub, C. Malvy, E. Fattal, P. Couvreur
https://www.researchgate.net/publication/6838406_Toub_N_Malvy_C_Fattal_E_and_Couvreur_P_Innovative_nanotechnologies_for_the_delivery_of_oligonucleotides_and_siRNA_Biomed_Pharmacother_60_607-620
Toub, N, Malvy, C, Fattal, E and Couvreur, P. Innovative nanotechnologies for the delivery of oligonucleotides and siRNA. Biomed Pharmacother 60: 607-620
https://core.ac.uk/display/75818746
Innovative nanotechnologies for the delivery of oligonucleotides and siRNA. ... Among these short nucleic acids an important class of therapeutic agents is antisense oligonucleotides and siRNAs. ... This review focuses on the recent developments in the design of nanotechnologies to improve the delivery of antisense oligonucleotides and siRNAs ...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2697810/
Antisense oligonucleotides and small interfering RNA have enormous potential for the treatment of a number of diseases, including cancer. However, several impediments to their widespread use as drugs still have to be overcome: in particular their lack of stability in physiological fluids and their poor penetration into cells.
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2475625/
Jun 16, 2008 · The potential use of antisense and siRNA oligonucleotides as therapeutic agents has elicited a great deal of interest. However, a major issue for oligonucleotide-based therapeutics involves effective intracellular delivery of the active molecules.Author: Rudy Juliano, Md. Rowshon Alam, Vidula Dixit, Hyumin Kang
https://www.liebertpub.com/doi/abs/10.1089/oli.2004.14.239
Innovative nanotechnologies for the delivery of oligonucleotides and siRNA. Biomedicine & Pharmacotherapy, Vol. 60, No. 9. Inhibition of cervical cancer cell growth in vitro and in vivo with lentiviral-vector delivered short hairpin RNA targeting human papillomavirus E6 and E7 oncogenes.Author: Ming Jiang, Carlos P. Rubbi, Jo Milner
https://www.researchgate.net/scientific-contributions/35026737_Nedjma_Toub
Nedjma Toub's 4 research works with 188 citations and 209 reads, including: Toub, N, Malvy, C, Fattal, E and Couvreur, P. Innovative nanotechnologies for the delivery of oligonucleotides and siRNA.
https://academic.oup.com/nar/article/36/12/4158/1132931
Jun 16, 2008 · An interesting variation on delivery via lipid conjugation is embodied in a recent report on α-tocopherol modified siRNA; this lipidic material also promotes siRNA delivery via binding to serum proteins and lipoproteins, but may involve a different set of binding partners . In vivo delivery of oligonucleotides using nanocarriersAuthor: Rudy Juliano, Md. Rowshon Alam, Vidula Dixit, Hyumin Kang
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