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https://www.researchgate.net/publication/26332535_Inner_Blood-Retinal_Barrier_Transporters_Role_of_Retinal_Drug_Delivery
Download Citation Inner Blood-Retinal Barrier Transporters: Role of Retinal Drug Delivery The inner blood-retinal barrier (inner BRB) forms complex tight junctions of retinal capillary ...
https://link.springer.com/article/10.1007%2Fs11095-009-9930-2
Jul 01, 2009 · The inner blood-retinal barrier (inner BRB) forms complex tight junctions of retinal capillary endothelial cells to prevent the free diffusion of substances between the circulating blood and the... Inner Blood-Retinal Barrier Transporters: Role of Retinal Drug Delivery SpringerLinkAuthor: Ken-ichi Hosoya, Masanori Tachikawa
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3225029/
The nutrient supply to the retina from the circulating blood is regulated by a variety of transporters expressed at the blood-retinal barrier (BRB). The BRB is formed by complex tight junctions of retinal capillary endothelial cells (inner BRB) and retinal pigment epithelial cells (RPE, outer BRB) (Hosoya and Tachikawa, 2009). Since nicotinic ...Author: Masanori Tachikawa, Masanori Tachikawa, Koji Murakami, Pamela Moore Martin, Ken Ichi Hosoya, Vadivel...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6010371/
Jun 18, 2018 · As noted above, the passage of a drug is prohibited by the blood-retinal barrier, especially in the case of drug delivery to the posterior segment of the eye where the direction of drug penetration is opposite to the direction of intraocular liquid circulation. Despite lower efficacy, the systemic route still presents an attractive strategy ...Author: Sibo Jiang, Yesenia L Franco, Yan Zhou, Jianjun Chen
https://link.springer.com/chapter/10.1007%2F978-1-4614-4711-5_4
Jan 23, 2014 · Abstract. The inner blood-retinal barrier (inner BRB) is created by complex tight junctions of retinal capillary endothelial cells. Although this barrier prevents the free diffusion of substances between the circulating blood and the neural retina, the inner BRB efficiently supplies nutrients to the retina and removes endobiotics and xenobiotics from the retina to maintain a constant milieu in ...Author: Ken-ichi Hosoya, Masanori Tachikawa
https://www.researchgate.net/publication/325717092_Role_of_Blood_Retinal_Barrier_in_Drug_Absorption
The blood-retinal barrier is the one of the earliest retinal changes in diabetes. The blood retinal barrier is a physiological barrier that regulates ion, protein and water flux in inner and outer ...
https://www.deepdyve.com/lp/springer-journals/inner-blood-retinal-barrier-transporters-role-of-retinal-drug-delivery-0AfppCvfOS
Jul 01, 2009 · Read "Inner Blood-Retinal Barrier Transporters: Role of Retinal Drug Delivery, Pharmaceutical Research" on DeepDyve, the largest online rental service for scholarly research with thousands of academic publications available at your fingertips.
https://www.sciencedirect.com/topics/medicine-and-dentistry/blood-retinal-barrier
Gisèle Soubrane, Gabriel Coscas, in Retina (Fifth Edition), 2013. Blood–retinal barrier. The blood–retinal barrier (BRB) is a particularly restrictive physiological barrier that regulates the flow of nutrients, metabolic waste products, ions, proteins, and water flux into and out of the retina.
https://www.touchophthalmology.com/the-blood-retinal-barrier-in-retinal-disease/
The blood–ocular barriers play a fundamental role in the preservation and maintenance of the appropriate environment for optimal visual cell function. 1 The blood–ocular barriers include two main barrier systems – the blood–aqueous barrier and the blood–retinal barrier (BRB) – which are fundamental to keeping the eye as a privileged ...
https://www.sciencedirect.com/science/article/pii/S1359644618305117
Although suitable drugs might be available in some cases, the delivery of these compounds into the eye and across the blood–retinal barrier remains a significant challenge for therapy development. Here, we review the routes of drug administration to the retina and highlight different options for drug delivery to the photoreceptor cells.Author: Erico Himawan, Per Ekström, Matej Buzgo, Pieter Gaillard, Einar Stefánsson, Valeria Marigo, Thorstei...
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