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https://www.sciencedirect.com/science/article/pii/S0169409X18300462
Although numerous injectable hydrogels have been developed for drug delivery and wound repair, our ability to synthetically replicate the complexities of the native ECM are still unrefined at best. Ultimately, in order to develop broadly applicable hydrogels we must accomplish three goals.Author: Robert Dimatteo, Nicole J. Darling, Tatiana Segura
https://www.sciencedirect.com/science/article/pii/S0142941819320811
Injectable hydrogels show promising properties as carrier for topical and localized drug delivery. The ability of 3D encapsulation contributes the functions of injectable hydrogel for tissue engineering. The balance among mechanical property, carrier capacity and processability is of important to an injectable hydrogel.Author: Yining Sun, Ding Nan, Haiqiang Jin, Xiaozhong Qu
https://www.sciencedirect.com/science/article/pii/S1359644616302562
Generally, injectable hydrogel-based drug delivery systems are found to be more efficacious than the conventional systemic chemotherapy in terms of cancer treatment.Author: Mohammad Norouzi, Bahareh Nazari, Donald W. Miller
https://wyss.harvard.edu/technology/injectable-alginate-hydrogels-for-medical-applications/
Injectable cryogels for tunable drug release Cryogels are hydrogels whose shape and other properties can be changed by altering the conditions under which they are frozen, and are thus an attractive option for creating drug delivery systems.
https://www.mdpi.com/2073-4360/12/4/884
1 day ago · Injectable, covalently cross-linked hydrogels have been widely investigated in drug delivery systems due to their superior mechanical properties and long-term stability. Conventional covalently cross-linked hydrogels are formed by chemical reactions that may interfere with natural biochemical processes.
https://pubs.acs.org/doi/abs/10.1021/acsami.6b00959
Severe side effects of cancer chemotherapy prompt developing better drug delivery systems. Injectable hydrogels are an effective site-target system. For most of injectable hydrogels, once delivered in vivo, some properties including drug release and degradation, which are critical to chemotherapeutic effects and safety, are challenging to monitor.Author: Jia Liu, Chao Qi, Kaixiong Tao, Jinxiang Zhang, Jian Zhang, Luming Xu, Xulin Jiang, Yunti Zhang, Lei...
https://www.sciencedirect.com/science/article/pii/S014181301500447X
In addition injectable hydrogels have received substantial in drug delivery applications since many years as they can be used as injectable controlled release vehicles for confined drug delivery. These injectable delivery systems acquire various advantages including ease of application, localized delivery in case of site-specific action, extended delivery periods, enhanced patient comfort and reduced body drug dosage by lessening unwanted side effects that may occur in systemic delivery , .Author: Sadia Atta, Shaista Khaliq, Atif Islam, Irtaza Javeria, Irtaza Javeria, Tahir Jamil, Muhammad Maksho...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5898614/
A family of β-hairpin peptides (namely, MAX peptides) has been developed to make injectable hydrogels for drug delivery 51,52. These peptides contain two blocks of alternating hydrophobic and charged amino acids in the form of long fibrils (up to 200 nm) that can undergo a sol–gel transition.Author: Jianyu Li, David J. Mooney
https://www.sciencedirect.com/science/article/pii/S0032386108000487
Hydrogels used in drug delivery are usually formed outside of the body and impregnated with drugs before placement of the hydrogel–drug complex in the body. A wide range of cross-linking strategies can be used, including UV photopolymerization and various chemical cross-linking techniques.Author: Todd R. Hoare, Daniel S. Kohane
https://blafar.com/products/injectable-hydrogel/
Injectable Hydrogels for Translational Medicine Blafar Ltd. provides a series of advanced injectable hydrogel systems as the optimal microenvironments for customized cell culture and regenerative medicine. These biocompatible injectable hydrogels are based on precisely designed functionalized extracellular matrix (ECM)-based biopolymers and/or ...
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