We have collected information about Inhaled Drug Delivery For Tuberculosis Therapy for you. Follow the links to find out details on Inhaled Drug Delivery For Tuberculosis Therapy.
https://link.springer.com/article/10.1007/s11095-009-9957-4
Sep 03, 2009 · Administering drugs by the pulmonary route to the lungs allows higher drug concentrations in the vicinity of these lesions. Supplementing conventional therapy with inhaled anti-TB therapy may allow therapeutic concentrations of drug to penetrate effectively into lung lesions and treat the resident mycobacteria.Author: Pavan Muttil, Chenchen Wang, Anthony J. Hickey
https://www.rti.org/publication/inhaled-drug-delivery-tuberculosis-therapy
Apr 20, 2017 · Inhaled Drug Delivery for Tuberculosis Therapy. One third of the world population is infected with tuberculosis (TB), and new infections occur at a rate of one per second. The recent increase in the emergence of drug-resistant strains of Mycobacterium tuberculosis and the dearth of anti-TB drugs is threatening the future containment of TB.Author: Pavan Muttil, Chenchen Wang, Anthony J. Hickey
https://www.future-science.com/doi/10.4155/tde-2017-0050
Sep 25, 2017 · Specifically, for inhaled TB treatment, drugs should target alveolar macrophages that harbor microorganisms and/or maintain high drug concentration at the infection site in the lung . Inhaled drug delivery offers this prospect and has the potential to achieve high concentrations of pharmacologic agents in the lungs, while producing adequate systemic concentrations through …Author: Daniela Traini, Paul M Young
https://www.researchgate.net/publication/41564123_Inhaled_Drug_Delivery_for_Tuberculosis_Therapy
Microparticulate drug delivery to the lung for TB therapy. A The location and morphology of a granuloma in a diseased lung. B Lung alveoli surrounded by blood vessels.
https://www.researchgate.net/profile/Pavan_Muttil/publication/41564123_Inhaled_Drug_Delivery_for_Tuberculosis_Therapy/links/595eb6c30f7e9b8194b725f6/Inhaled-Drug-Delivery-for-Tuberculosis-Therapy.pdf
Supplementing conventional therapy with inhaled anti-TB therapy may allow therapeutic concentrations of drug to penetrate effectively into lung lesions and treat the resident mycobacteria.
https://www.cabdirect.org/cabdirect/abstract/20103031533
The recent increase in the emergence of drug-resistant strains of Mycobacterium tuberculosis and the dearth of anti-TB drugs is threatening the future containment of TB. New drugs or delivery systems that will stop the spread of TB and slow down or prevent the development of drug-resistant strains are urgently required.Author: Pavan Muttil, Chenchen Wang, Anthony J. Hickey
https://www.sciencedirect.com/science/article/abs/pii/S1472979210000922
As distinct from vaccine delivery formulations, inhalations intended for drug delivery are presumed to require chronic and repeated administration of larger amounts of material. This review seeks to summarize the consensus on the ways and means available or under development, to deliver different anti-TB agents as aerosols for inhalation.Author: Amit Misra, Anthony J. Hickey, Carlo Rossi, Gerrit Borchard, Hiroshi Terada, Kimiko Makino, P. Berna...
https://onlinelibrary.wiley.com/doi/10.1002/9781118943182.ch11
Drugs that inhibit resistance mechanisms of the pathogen, such as drug efflux pumps, are also proposed as candidates for inclusion in combination therapy of multiple‐drug‐resistant (MDR) TB. Drug Delivery Systems for Tuberculosis Prevention and TreatmentAuthor: Sanketkumar Pandya, Anuradha Gupta, Rajeev Ranjan, Madhur Sachan, Atul Kumar Agrawal, Amit Misra
https://www.future-science.com/doi/pdfplus/10.4155/tde-2017-0050
inhaled therapy may hold the key as a potential new delivery mode that has improved health benefits. These are likely to include reduced treatment times and possibly limited insurgence of drug resistance. Specifically, for inhaled TB treatment, drugs should target alveolar macrophages that harbor microorganisms and/or maintain
https://www.sciencedirect.com/science/article/pii/S1472979210000922
Inhaled drug delivery offers opportunities to administer anti-TB agents or modulators of innate immune function that might not be amenable to conventional methods of drug delivery through oral or …Author: Amit Misra, Anthony J. Hickey, Carlo Rossi, Gerrit Borchard, Hiroshi Terada, Kimiko Makino, P. Berna...
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