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https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4334339/
Feb 12, 2015 · The STACCATO ® is a novel breath-actuated inhalation delivery system, which uses heat to vaporize a thin film of the drug, which later condenses in the lungs into droplets or particles depending on the nature of the drug.78 In that case, the drug is dissolved in volatile solvent/solvent mixture which is sprayed over a metal substrate such as zinc halides. The best drug candidates for …Author: Mariam Ibrahim, Rahul Verma, Lucila Garcia-Contreras
https://www.meddeviceonline.com/doc/developing-a-smart-inhaler-for-optimal-drug-delivery-0001
Dec 16, 2019 · Historically, inhalation drug delivery was limited to the treatment and management of respiratory diseases, such as asthma or chronic obstructive pulmonary disease.
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1884307/
Apr 19, 2002 · The type of inhalation devices and drug formulation are determinants of the drug aerosol's particle size. In Part II, the inhalational delivery devices’ and drug formulations’ effect on the therapeutic effectiveness of aerosolized drug therapy will be reviewed.Author: N. R. Labiris, M. B. Dolovich
https://www.inomax.com/inomax-delivery-systems/inomax-devices
The INOmax DS IR Plus Delivery Systems deliver INOMAX (nitric oxide) gas, for inhalation. The INOmax DS IR Plus Delivery Systems must only be used in accordance with the indications, usage, contraindications, and warnings and precautions described in the INOMAX package inserts and labeling. The approved patient population is limited to neonates.
https://www.sciencedirect.com/topics/pharmacology-toxicology-and-pharmaceutical-science/pulmonary-drug-delivery
Inhalable nanoparticles in the solid-state as inhalable powders for targeted pulmonary delivery offer unique advantages and are a new area of research. However, there are limitations. Toxicity of nanoparticles (i.e., nanotoxicity), polymers, and other excipients is critical for the development of safe inhalable dry powder inhalation formulations.
https://www.catalent.com/specialty/inhalation/
As a leader in inhalation product development, we offer development services throughout your product’s lifecycle: Preformulation With the state-of-art technologies and a team of experienced and talented preformulation scientists, your product can be optimized for success.
https://www.ncbi.nlm.nih.gov/pubmed/15737247/
Inhalation is a very old method of drug delivery, and in the 20th century it became a mainstay of respiratory care, known as aerosol therapy. Use of inhaled epinephrine for relief of asthma was reported as early as 1929, in England.Author: Joseph L Rau
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4839019/
Apr 20, 2016 · The lungs allow for efficient drug delivery as they have a large surface area and are well vascularized . For example, inhaled nicotine is readily absorbed across the pulmonary epithelia into the bloodstream where it can exert its psychotropic effects on the brain .Author: Robert C. Fellner, Shawn T. Terryah, Robert Tarran
https://www.vero-biotech.com/
Inhaled Nitric Oxide Delivery Inhaled Nitric Oxide (NO) has the potential to benefit patients, from neonates to adults with a range of cardiopulmonary conditions characterized by pulmonary hypertension – whether the patients are in critical care hospital settings, chronic care facilities, or even in the home.
https://www.ncbi.nlm.nih.gov/pubmed/28504252
In contrast, inhalation routes permit the delivery of drugs directly to the lungs providing high local concentrations that may enhance the anti-tumor effect while alleviating systemic adverse effects.Author: Sharad Mangal, Wei Gao, Tonglei Li, Qi (Tony) Zhou
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