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https://www.catalent.com/specialty/inhalation/
Catalent combines decades of project with all pulmonary and nasal dosage forms including MDIs, DPIs, nasal sprays and solutions/suspensions for inhalation. Speed is delivered by workflows that have been continuously refined and applied to programs at all stages of development, including: Formulation feasibility, development and optimization
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6523761/
Apr 01, 2019 · The lungs offer a large surface for drug absorption, and the inhalation of aerosolized drugs are a well-established therapeutic modality for local treatment of lung conditions. Nanoparticle-based drug delivery platforms are gaining importance for use through the pulmonary route.Author: Tina Gulin-Sarfraz, Sofia Jonasson, Elisabeth Wigenstam, Eva von Haartman, Anders Bucht, Jessica M. ...
https://www.ondrugdelivery.com/overview-dry-powder-inhalation-systemic-drug-delivery/
Kane C, O’Neil K, Conk M, Picha K, “Inhalation delivery of protein therapeutics”. Inflammation & Allergy – Drug targets, 2013, Vol 12, pp 81-87. Mumenthaler M, Hsu CC, Pearlman R, “Feasibility study on spray-drying protein pharmaceuticals: recombinant human growth …
https://www.pnas.org/content/98/20/11103
Sep 25, 2001 · Thus the present study demonstrates, both in vitro and in vivo, the initial feasibility of inhalation delivery of proteins from their suspensions in ethanol. Inhalation of relevant quantities of aerosolized ethanol by itself caused no appreciable acute toxicity.Author: W. S. Choi, G. G. K. Murthy, D. A. Edwards, R. Langer, A. M. Klibanov
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC58690/
Sep 25, 2001 · Inhalation delivery of proteins from ethanol suspensions is free of many inherent drawbacks of the aqueous and dry powder approaches. It is amenable to the use of standard nebulizers and should be applicable to the delivery of other macromolecular therapeutics, …Author: W. S. Choi, G. G. K. Murthy, D. A. Edwards, R. Langer, A. M. Klibanov
https://s3.amazonaws.com/cpsl-web/kc/pdfs/Capsugel_Inhalation_Drug_Delivery.pdf
Inhalation formulations for nasal and pulmonary drug delivery continue to grow driven by the prevalence of respiratory diseases especially COPD (chronic obstructive pulmonary disease). Capsugel Dosage Form Solutions offers an inhalation drug delivery formulations based on proven spray-dried dispersion technology pioneered by Bend Research.
https://www.nature.com/articles/nrcardio.2018.11
Inhalation of peptide-loaded nanoparticles is a feasible approach for targeted delivery of drugs to the heart, according to a new study published in Science Translational Medicine. Drugs for ...Author: Gregory B. Lim
After the initial feasibility study, the path to IND will often depend on conducting IND-enabling inhalation toxicology studies and optimizing the delivery platform for a specific compound. In addition, particle size optimization is often performed in order to assure deep lung delivery.
https://www.pnas.org/content/pnas/98/20/11103.full.pdf
Inhalation delivery of proteins from ... feasibility of such an alternative, which involves the nebulization of solid proteins suspended in a common nonaqueous solvent, namely ethanol. Although proteins (e.g., enzymes) have been conventionally used in their natural aqueous media, recentAuthor: W. S. Choi, G. G. K. Murthy, D. A. Edwards, R. Langer, A. M. Klibanov
https://www.marketwatch.com/press-release/inhalation-drug-delivery-devices-market-demand-analysis-by-top-key-players-gsk-3m-astrazeneca-novartis-aptar-boehringer-ingelheim-2020-02-27
Feb 27, 2020 · Feb 27, 2020 (Stockestic via COMTEX) -- An analysis of Global Inhalation Drug Delivery Devices Market has been provided within the latest report …
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