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https://www.sciencedirect.com/science/article/pii/S0169409X06001633
Nov 15, 2006 · Industrial perspective in ocular drug delivery ... a drug delivery module and (c) a platform. The drug in Ocusert is pilocarpine base. The drug delivery module consists of: (a) a drug reservoir, and a carrier material namely, alginic acid; (b) a rate controller namely, ethylene/vinyl acetate (EVA) copolymer membrane; (c) an energy source ...Author: Yusuf Ali, Kari Lehmussaari
https://www.researchgate.net/publication/6717615_Industrial_perspective_in_ocular_drug_delivery
Ocular drug delivery studies in past decades have employed in vivo animal models, such as rabbits, and have been conducted in vitro by using isolated rabbit ocular tissues, which also implies the ...
https://www.sciencedirect.com/science/article/abs/pii/S0169409X06001633
In the development of a commercial drug product, the formulator must consider various perspectives. The bioavailability of the active drug substance is often the major hurdle to overcome. In the past it has been common to add viscosity-enhancing agents or mucoadhesive polymers into formulations to improve ocular bioavailability.Author: Yusuf Ali, Kari Lehmussaari
https://www.ncbi.nlm.nih.gov/pubmed/17079049
Nov 15, 2006 · Industrial perspective in ocular drug delivery. Ali Y(1), Lehmussaari K. Author information: (1)Santen Inc, Napa, CA 94559, USA. [email protected] In the development of a commercial drug product, the formulator must consider various perspectives. The bioavailability of the active drug substance is often the major hurdle to overcome.Author: Yusuf Ali, Kari Lehmussaari
https://www.deepdyve.com/lp/elsevier/industrial-perspective-in-ocular-drug-delivery-rAoBCncwSv
Nov 15, 2006 · Industrial perspective in ocular drug delivery Industrial perspective in ocular drug delivery Ali, Yusuf; Lehmussaari, Kari 2006-11-15 00:00:00 In the development of a commercial drug product, the formulator must consider various perspectives. The bioavailability of the active drug substance is often the major hurdle to overcome.
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3712243/
Jun 27, 2013 · Delivery of drugs into eyes using conventional drug delivery systems, such as solutions, is a considerable challenge to the treatment of ocular diseases. Drug loss from the ocular surface by lachrymal fluid secretion, lachrymal fluid-eye barriers, and ...Author: Rahul Rama Hegde, Anurag Verma, Amitava Ghosh
http://www.recentpatentsondrugdeliveryformulation.com/
Aims & Scope. Recent Patents on Drug Delivery & Formulation publishes review and research articles, drug clinical trial studies and guest edited thematic issues on recent patents on drug delivery and formulation.A selection of important and recent patents on drug delivery and …
https://www.nature.com/articles/srep44229
Mar 14, 2017 · Creation of nano eye-drops and effective drug delivery to the interior of the eye. ... K. Industrial perspective in ocular drug delivery. Adv. Drug Deliv. Rev. 58, 1258–1268 (2006). CAS;Author: Yoshikazu Ikuta, Shigenobu Aoyagi, Yuji Tanaka, Kota Sato, Satoshi Inada, Yoshitaka Koseki, Tsunenob...
https://www.researchgate.net/publication/283345976_An_Insight_into_Ocular_Drug_Delivery_System
An Insight into Ocular Drug Delivery System. ... Industrial 25 Perspective in ocular drug delivery Advanced Drug Preliminary pharmacokinetic model of pilocarpine Delivery Reviews, 58: 1258-1268 ...
https://www.tandfonline.com/doi/abs/10.1517/17425247.2011.542142
May 20, 2008 · Importance of the field: A major challenge emanating in the design of topical ophthalmic preparations is their short precorneal residence time. Retention of a drug delivery system in the front of the eye is thus desirable. One solution identified to address this concern is a retentive system that can preferably be delivered in a liquid drop form and ultimately remain attached to the corneal ...Author: Lisa C du Toit, Viness Pillay, Yahya E Choonara, Thirumala Govender, Trevor Carmichael
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