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https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3576846/
Implantable drug-delivery systems provide new means for achieving therapeutic drug concentrations over entire treatment durations in order to optimize drug action. This article focuses on new drug administration modalities achieved using implantable drug-delivery systems that are enabled by micro- and nano-fabrication technologies, and microfluidics.Author: Ellis Meng, Tuan Hoang
https://promedmolding.com/implantable-drug-delivery-devices-overview/
Dec 18, 2017 · Implantable drug delivery devices offer several advantages over conventional oral or parenteral dosage forms. First, implantable devices allow site specific drug administration where the drug is most needed. Examples include implants used in the treatment of brain tumors (Gliadel® wafer) or prostate cancer (Lupron® depot).
https://www.sciencedirect.com/science/article/pii/B9780128136652000132
Mechanisms of Drug Release From Implantable Drug Delivery Systems Most passive implanted DDSs are based on four basic delivery mechanisms: matrix degradation, controlled swelling, osmotic pumping, and passive diffusion.Author: Anoop Kumar, Jonathan Pillai
https://www.aao.org/eyenet/article/promise-of-implantable-drug-delivery-systems
Requiring conjunctival dissection, it is implanted through a 25-gauge needle and self-anchors in the sclera, delivering the drug for up to two years. The implant’s helical coil increases the surface area for drug delivery and uses a polymer coating that’s commonly used for cardiac stents.
https://www.sciencedirect.com/science/article/pii/B9780081025482000056
Implantable drug delivery systems provide extended release of a drug for the desired duration, usually over timespans of months and years. Placement of implantable devices routinely requires a specific insertion device for placement rather than a surgical procedure.Author: Ian Major, Sarah Lastakchi, Maurice Dalton, Christopher McConville
https://www.pharmatutor.org/articles/review-implantable-drug-delivery-system
Therefore, drug delivery systems were developed to optimize the therapeutic properties of drug products and render them more safe, effective, and reliable. In comparison with many of the other drug delivery systems, implantable pumps and implants for variable rate delivery are at …
https://www.researchgate.net/publication/319327771_Implantable_drug_delivery_systems_An_Overview
The concept of implantable drug delivery systems (IDDSs) in modern medicine. may be traced to Deansby and Parkes who, in 1938, subcutaneously (SC) implanted compressed pellets of crystalline estrone to study their effect upon. Nanostructures for the Engineering of Cells, Tissues and Organs.
http://www.authorstream.com/Presentation/pavan22raju-1931893-implants-drug-delivery-systems/
Sep 15, 2013 · Implantable drug delivery systems are designed to transmit drugs and fluids into the bloodstream without the repeated insertion of needles. Implantable drug delivery systems are placed completely under the skin usually in a convenient but inconspicuous location. The patient is aware of only a small bump under the skin.
http://sphinxsai.com/2012/pharm/PHARM/PT=40(280-292)JM12.pdf
Fully implantable drug delivery devices are desirable where alternate forms of delivery are not preferred or not possible. These devices allow drugs to be delivered at efficacious locations and rates without the issue of patient compliance. An advanced implantable system can be used to precisely control the rate of drug delivery.
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