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https://www.medgadget.com/2016/06/intarcia-medici-tiny-implantable-pump-drug-delivery.html
Intarcia Therapeutics, a company based in Boston, MA, is showing off its new Medici Drug Delivery System. The package consists of a drug pump about the ... a Tiny Implantable Pump for Drug ...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3576846/
Implantable drug-delivery devices. Implantable drug infusion pumps have been in use for many years and for both preclinical and clinical applications. Typical implantable systems possess three fundamental components: drug container, drug release mechanism and an implantable packaging.Author: Ellis Meng, Tuan Hoang
https://promedmolding.com/implantable-drug-delivery-devices-overview/
Dec 18, 2017 · Implantable drug delivery devices offer several advantages over conventional oral or parenteral dosage forms. First, implantable devices allow site specific drug administration where the drug is most needed. Examples include implants used in the treatment of brain tumors (Gliadel® wafer) or prostate cancer (Lupron® depot).
https://www.sciencedirect.com/science/article/pii/B9780128136652000132
With advances in microelectronics since the 1970s, remote control over delivery rates or integration of implantable sensors to create feedback-controlled drug delivery is now feasible. Implantable pumps primarily utilize osmosis, propellant-driven fluids, or electromechanical drives to generate pressure gradients and enable controlled drug ...Author: Anoop Kumar, Jonathan Pillai
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3149148/
Successful drug delivery using implantable pumps may be found in over 12,500 published articles. Their versatility in delivering continuous infusion, intermittent or complex infusion protocols acutely or chronically has made them ubiquitous in drug discovery and basic research.
https://www.sciencedirect.com/topics/nursing-and-health-professions/implantable-pump
Implantable pumps allow physicians to administer opiate analgesics directly into the cerebrospinal fluid (CSF). The pumps are programmable so that the treating physicians can adjust dosages and delivery rates. The reservoir will have to be refilled on an intermittent basis: this is achieved by a percutaneous injection into the reservoir.
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3348997/
With the adjustability in flow rate offered by our system, a multitude of pharmacodynamic responses can be studied in a way that has not been possible until now. We also demonstrate, for the first time, an implantable MEMS micropump system for controlled dose, timing, and location of drug delivery in mice.Author: Heidi Gensler, Roya Sheybani, Po-Ying Li, Ronalee Lo Mann, Ellis Meng
https://www.fda.gov/medical-devices/safety-communications/use-caution-implanted-pumps-intrathecal-administration-medicines-pain-management-fda-safety
Nov 14, 2018 · Recommendations and info about the risks of using medications delivered into the spinal fluid to treat or manage pain that are not approved for implanted pumps.
https://www.researchgate.net/publication/319327771_Implantable_drug_delivery_systems_An_Overview
Implantable drug delivery systems offer physicians the choice of precision delivery, either locally or into systemic circulation, while guaranteeing optimal dosing over the course of treatment.The ...
https://www.neuromodulation.com/fact_sheet_intrathecal_drug_delivery
Intrathecal drug delivery systems are implanted pumps that target pain relief or anti-spasm medication to an area of the spine that relays signals between an affected area of the body and the brain. Persons with chronic pain or muscle spasms may be considered for such a device if, over time, the medications they have been taking have become ...
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