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https://www.researchgate.net/publication/237882931_Hydrophobic_modifications_of_cationic_polymers_for_gene_delivery
Cationic polymers are the subject of intense research as non-viral gene delivery systems, due to their flexible properties, facile synthesis, robustness, and proven gene delivery efficiency.
https://www.sciencedirect.com/science/article/pii/S0079670010000468
This review discusses recent studies on the hydrophobic modifications of cationic polymers for gene delivery. The effects of the hydrophobic modifications are discussed in terms of critical issues in the gene delivery process, such as gene encapsulation, adsorption to cell membrane, serum inhibition, gene dissociation, cytotoxicity, and tissue ...Author: Zonghua Liu, Ziyong Zhang, Changren Zhou, Yanpeng Jiao
https://www.deepdyve.com/lp/elsevier/hydrophobic-modifications-of-cationic-polymers-for-gene-delivery-gXgGNwcfD2
Sep 01, 2010 · Read "Hydrophobic modifications of cationic polymers for gene delivery, Progress in Polymer Science" on DeepDyve, the largest online rental service for scholarly research with thousands of academic publications available at your fingertips.
https://www.sciencedirect.com/science/article/pii/S0142961211002432
Effects of hydrophobic and hydrophilic modifications on gene delivery of amphiphilic chitosan based nanocarriers. ... due to significantly disparate requirements of hydrophobic drug delivery from those of hydrophilic nucleic acid, ... Z. Zhang, C. Zhou, Y. JiaoHydrophobic modifications of cationic polymers for …Author: Bingqing Wang, Chunbai He, Cui Tang, Chunhua Yin
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3959121/
Oct 10, 2011 · Other studies have looked at modifying cationic polymers with hydrophobic moieties to increase transfection efficacy. Hydrophobic modification of polycations has been shown to be beneficial for gene delivery for a variety of reasons.Author: Joel C. Sunshine, Marib I. Akanda, David Li, Kristen L. Kozielski, Jordan J. Green
https://www.nature.com/articles/nrd1775
Jul 01, 2005 · Design and development of polymers for gene delivery. ... The use of cationic lipids for gene delivery was first reported by ... Most of the modifications reduced the gene-delivery activity of …Author: Daniel W. Pack, Allan S. Hoffman, Suzie Pun, Patrick S. Stayton
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3857137/
Oct 22, 2013 · The 50B polymer had optimally-balanced cationic and hydrophobic content in the core-forming block and formed polyplex NPs with ... Zhang S, Wang B, Cui S, Yan J. Toxicity of Cationic Lipids and Cationic Polymers in Gene Delivery. J Control Release. ... Jiao Y. Hydrophobic Modifications of Cationic Polymers for Gene Delivery. ProgPolym Sci. 2010 ...Author: Christopher E. Nelson, James R. Kintzing, Ann Hanna, Joshua M. Shannon, Mukesh K. Gupta, Craig L. Du...
https://www.hindawi.com/journals/jnm/2011/742895/
3.4. Hydrophobic Modifications of Cationic Polymers. For gene delivery, it has been widely reported that hydrophobic modification of cationic polymers could improve the interaction between vectors, resulting in more efficient escape by lysis of the endosomes and therefore higher …Author: Shutao Guo, Leaf Huang
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