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https://www.sciencedirect.com/science/article/pii/S0032386108000487
Hydrogels used in drug delivery are usually formed outside of the body and impregnated with drugs before placement of the hydrogel–drug complex in the body. A wide range of cross-linking strategies can be used, including UV photopolymerization and various chemical cross-linking techniques.Author: Todd R. Hoare, Daniel S. Kohane
https://www.nature.com/articles/natrevmats201671
Oct 18, 2016 · Hydrogel delivery systems can leverage therapeutically beneficial outcomes of drug delivery and have found clinical use. Hydrogels can provide spatial and …Author: Jianyu Li, David J. Mooney
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5898614/
Hydrogel delivery systems can leverage therapeutically beneficial outcomes of drug delivery and have found clinical use. Hydrogels can provide spatial and temporal control over the release of various therapeutic agents, including small-molecule drugs, macromolecular drugs and cells. Owing to their ...Author: Jianyu Li, David J. Mooney
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3568318/
Feb 05, 2013 · There are several relevant extensions of the technology platform. For example, more than one drug could be tethered to a hydrogel by one or more individually tuned linkers to provide a delivery system that releases the drug combination at the same or different rates.Author: Gary W. Ashley, Jeff Henise, Ralph Reid, Daniel V. Santi
https://www.researchgate.net/publication/224319682_As_A_Review_on_Hydrogels_as_Drug_Delivery_in_the_Pharmaceutical_Field
Hydrogel is a network of polymer chains that are water-insoluble, sometimes found as a colloidal gel in which water is the dispersion medium. Hydrogels are crosslinked polymer networks that absorb ...
http://www.orientjchem.org/vol29no3/hydrogels-smart-materials-for-drug-delivery/
The pharmaceutical industry has been developing hydrogel based drug delivery system in an advanced manner by tuning the structure, shape and surface modifications of the biopolymers. The present review highlights the role of hydrogels in drug delivery. It also highlights the use of important polymers and their applications in drug delivery.
https://www.sciencedirect.com/science/article/pii/B9780128140338000035
Thermo- and pH-sensitive hydrogels are among the most investigated hydrogel-based drug-delivery systems, which sense the elevated temperature and low pH in the body, respectively , . Examples of stimulus-responsive hydrogel nanocomposites used as drug-delivery systems are shown in Table 3.2.Author: Débora F. Argenta, Talitha C. dos Santos, Angela M. Campos, Thiago Caon
https://pubs.acs.org/doi/10.1021/acs.molpharmaceut.9b01020
As an emerging drug carrier, hydrogels have been widely used for tumor drug delivery. A hydrogel drug carrier can cause less severe side effects than systemic chemotherapy and can achieve sustained delivery of a drug at tumor sites. In addition, hydrogels have excellent biocompatibility and biodegradability and lower toxicity than nanoparticle carriers. Smart hydrogels can respond to stimuli ...Author: Zhaoyi Sun, Chengjun Song, Chao Wang, Yiqiao Hu, Jinhui Wu
https://pubs.acs.org/doi/10.1021/acs.biomac.9b01290
Near-infrared (NIR) light-responsive, injectable hydrogels are among the most promising drug delivery systems for localized anticancer therapy owing to its minimally invasive administration and remote-controlled manner. However, most currently reported NIR-responsive hydrogels were usually generated through physical mixing of thermosensitive polymers and photothermal conversion agents. In this ...Author: Pengfei Sun, Ting Huang, Xiaoxiao Wang, Gaina Wang, Zhijia Liu, Zhijia Liu, Guosong Chen, Quli Fan
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