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https://www.sciencedirect.com/science/article/pii/S0939641115001654
For drug delivery applications the advantage of forming polymeric micelles are several, including: (i) the incorporation of hydrophobic drugs in the micelle core, (ii) the relatively high stability of the system and the tailoring of specific triggers for the drug release, (iii) the hydrophilic polymer forming the outer shell of the micelle could show peculiar drug targeting properties, as occurs for HA.Author: Giuseppe Tripodo, Adriana Trapani, Maria Luisa Torre, Gaetano Giammona, Giuseppe Trapani, Delia Mand...
http://dl.begellhouse.com/journals/3667c4ae6e8fd136,2dd88d8418cc6252,31dd004a3bb502ee.html
Hyaluronan (HA), an abundant nonsulfated glycosaminoglycan component of synovial fluid and the extracellular matrix, is an attractive building block for new biocompatible and biodegradable polymers that have applications in drug delivery, tissue engineering, and viscosupplementation.
https://www.sciencedirect.com/science/article/abs/pii/S0939641115001654
The aim of this review was to provide an overview of the existing recent literature on the use of HA and its derivatives for drug delivery and imaging. Notable attention is given to nanotheranostic systems obtained after conjugation of HA to nanocarriers as quantum dots, carbon nanotubes and graphene.Author: Giuseppe Tripodo, Adriana Trapani, Maria Luisa Torre, Gaetano Giammona, Giuseppe Trapani, Delia Mand...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6058522/
Mar 14, 2018 · The application of hyaluronic acid and its derivatives as carriers in drug delivery In view of the specific binding of hyaluronic acid to the receptors on the surface of cancer cells, its biodegradability and biocompatibility, the application of hyaluronic acid in the targeted drug delivery of anticancer drugs has made great progress.Author: Gangliang Huang, Hualiang Huang
https://www.drugs.com/cdi/hyaluronate-and-derivatives-injection-knee.html
Dec 26, 2019 · If you have an allergy to hyaluronic acid or any other part of hyaluronate and derivatives injection (knee). If you are allergic to hyaluronate and derivatives injection (knee); any part of hyaluronate and derivatives injection (knee); or any other drugs, foods, or substances. Tell your doctor about the allergy and what signs you had.5.8/10
https://www.researchgate.net/publication/313123174_Hyaluronate_and_its_derivatives_for_customized_biomedical_applications
HA has been used for drug delivery to enhance the blood circulation time of drugs with target-specificity to HA receptors in the body.
https://www.healthnet.com/static/general/unprotected/html/national/pa_guidelines/2225.pdf
Hyaluronate derivatives are indicated for the treatment of pain in osteoarthritis (OA) of the knee in patients who have failed to respond adequately to conservative non-pharmacologic therapy and to simple analgesics (e.g., acetaminophen) or non-steroidal anti-inflammatory drugs
https://www.researchgate.net/publication/268188533_Hyaluronic_Acid_in_Drug_Delivery_Systems
Particles and hydrogels by various methods using HA and HA derivatives as well as by con-jugation with other polymer have been the focus of many studies. Furthermore, the affinity of HA to the CD44 receptor which is overexpressed in various tumor cells makes HA an important means of cancer targeted drug delivery.
https://www.bcbst.com/mpmanual/Hyaluronan_Derivatives.htm
17 rows · Hyaluronan derivatives for clinical use are known as hyaluronate sodium or sodium …
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