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https://www.sciencedirect.com/science/article/pii/S0169409X19301425
Hyaluronic acid and its derivatives have been widely used in various drug delivery systems, such as nanoparticle drug delivery system, gel drug delivery system, cationic polymer gene carrier system, nano-emulsion delivery system, polyelectrolyte microcapsule drug delivery system, microsphere drug delivery system, film delivery system, and these various techniques gave a great flexibility . HA hydrogels are methods of gene delivery …Author: Alberto Passi, Davide Vigetti
https://www.sciencedirect.com/science/article/pii/0169409X9190008Z
HYALURONAN IN DRUG DELIVERY 303 The data on hyaluronan receptors and HA-BP indicate that there are several of these classes. (a) The first class is represented by a linking protein serving as a joint in the building of hyaluronan into the structure of connective tissue, particularly cartil- age.Author: Jaroslav Drobnik
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3551211/
Mar 30, 2012 · Increasing drug delivery to hypovascular and stroma-rich tumours is a promising strategy to circumvent therapeutic resistance in PDA. HA is an attractive target in the tumour microenvironment of PDA. The synergism of PEGPH20 and gemcitabine is of immediate clinical significance and provides support for investigational trials with this therapeutic combination.Author: Michael A Jacobetz, Derek S Chan, Albrecht Neesse, Tashinga E Bapiro, Natalie Cook, Kristopher K Fre...
https://www.tandfonline.com/doi/abs/10.1080/10717540590952555?needAccess=true
It is most frequently referred to as hyaluronan because it exists in vivo as a p... Hyaluronan: Pharmaceutical Characterization and Drug Delivery: Drug Delivery: Vol 12, No 6 Skip to Main ContentAuthor: Yong-Hong Liao, Stuart A. Jones, Ben Forbes, Gary P. Martin, Marc B. Brown
https://www.tandfonline.com/doi/abs/10.1080/10717540590952555
Oct 10, 2008 · The unique viscoelastic nature of hyaluronan along with its biocompatibility and nonimmunogenicity has led to its use in a number of cosmetic, medical, and pharmaceutical applications. More recently, HA has been investigated as a drug delivery agent for ophthalmic, nasal, pulmonary, parenteral, and dermal routes.Author: Yong-Hong Liao, Stuart A. Jones, Ben Forbes, Gary P. Martin, Marc B. Brown
https://www.researchgate.net/publication/7512849_Hyaluronan_Pharmaceutical_Characterization_and_Drug_Delivery
More recently, HA has been investigated as a drug delivery agent for ophthalmic, nasal, pulmonary, parenteral, and dermal routes.
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6058522/
Mar 14, 2018 · When hyaluronic acid is used as an antitumor drug delivery carrier to target tumor cells, the site of action is mainly CD44 receptor (Yu et al., 2013). CD44 receptor may exist a wide range of expression, the mutation itself reduces the selectivity of the …Author: Gangliang Huang, Hualiang Huang
https://www.drugs.com/mtm/hyaluronan.html
Nov 20, 2019 · Hyaluronan is similar to the fluid that surrounds the joints in your body. This fluid acts as a lubricant and shock absorber for the joints. Hyaluronan is used to treat knee pain caused by osteoarthritis. Hyaluronan is usually given after other arthritis medications have …6/10
Hyamedix is a Hyaluronan technology platform company specialized in the development and use of various forms of Hyaluronan for research, diagnostics, medical device and therapeutic (drug delivery/release) applications.
https://www.researchgate.net/publication/268188533_Hyaluronic_Acid_in_Drug_Delivery_Systems
Hyaluronic acid (HA) is a glycosaminoglycan found inside human body and distributed throughout the epithelial, connective, and neural tissues [13,14]. It is the main component of the extracellular matrix and the main ligand for CD44 and Receptor for Hyaluronan-Mediated Motility (RHAMM).
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