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https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3419303/
Injection of drugs through hollow microneedles is arguably the most powerful method of microneedle-based drug delivery that enables the greatest control over the amount and timing of drug delivery. Hollow microneedles can be briefly inserted into the skin for bolus injection or can be left in place for sustained infusion.Author: Yeu-Chun Kim, Yeu-Chun Kim, Yeu-Chun Kim, Jung-Hwan Park, Mark R. Prausnitz
https://www.3m.com/3M/en_US/drug-delivery-systems-us/technologies/microneedle/hollow-needle/
With a hollow microneedle length of 1500 micron combined with flexibility to deliver from 0.5 mL to 2 mL over a range of viscosities, 3M Hollow Microstructured Transdermal System provides an intradermal delivery option for your valuable biologic formulation.
https://www.3m.com/3M/en_US/drug-delivery-systems-us/technologies/microneedle/
3M Microneedle Drug Delivery Systems, which include Hollow Microneedle and Solid Microneedle technology, offer patient-friendly delivery solutions for vaccines or difficult-to-deliver biologics for particularly needle-phobic patients. By potentially reducing anxiety, microneedle delivery may improve patient compliance in some patient groups.
https://www.jstage.jst.go.jp/article/jsmbe/51/Supplement/51_M-38/_pdf
Hollow microneedles: a) close up of a needle, b) micro needle array; all shown needles are 500 µm tall and have a spa cing of 1 mm. The drug delivery capability of the fabricated microneedles has been tested in vitro by injection of 2.3 µmAuthor: Iman Mansoor, Jacqueline Lai, Dana Lambert, Jan Dutz, Urs Häfeli, Boris Stoeber
https://pubs.rsc.org/en/Content/ArticleLanding/2020/RA/D0RA00735H
With the limitation of present drug delivery, the demand for new delivery methods for psoriasis is in the spotlight. Thus, this review paper aims to provide a comprehensive statement about the microneedles, the progress of the microneedle application in the management of psoriasis and the clinical challenges.
https://www.sciencedirect.com/science/article/pii/S1773224717309589
Abstract There are exciting developments in the research domain regarding the use of ceramic microneedles (CMs) and hollow microneedles (HMNs) for transdermal drug delivery. Several microfabrication techniques (micromolding, microreplication, photopolymerization, etching, modified LIGA, etc) have been used to make these microneedle devices.Author: Kevin B. Ita
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3038673/
Hollow microneedles are needles of micron dimensions that can infuse fluid into tissue with excellent spatial targeting. Fabrication and characterization of hollow microneedles have been extensively studied for drug delivery to the skin (12–16), including recent human studies administering insulin and influenza vaccine .Author: Samirkumar R. Patel, Angela S. P. Lin, Henry F. Edelhauser, Mark R. Prausnitz
https://www.sciencedirect.com/science/article/pii/S0169409X03002394
Hollow microneedles In contrast to the solid microneedles discussed above, microneedles containing a hollow bore offer the possibility of transporting drugs through the interior of well-defined needles by diffusion or, for more rapid rates of delivery, by pressure-driven flow.Author: Mark R Prausnitz
https://www.techinasia.com/companies/micropoint-technologies#!
We design and manufacture solid and hollow microneedles for medical applications, which include transdermal and intradermal drug delivery, blood sampling for in-intro diagnostics and cosmetic ...
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