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https://pubs.acs.org/doi/abs/10.1021/bk-2006-0934.ch004
Jun 22, 2006 · Contramid® is a novel pharmaceutical excipient obtained by chemically and physically modifying a high-amylose corn starch. When a compressed tablet of Contramid® powder is placed in an aqueous medium, the material forms a hard gel displaying sponge-like viscoelastic properties.
https://www.sciencedirect.com/science/article/abs/pii/S0168365997002563
Cross-linked high amylose starches have been developed as excipients for the formulation of controlled-release solid dosage forms for the oral delivery of drugs. Advantages of this new class of excipients include cost-effectiveness, readily accessible industrial manufacturing technology, high active ingredient core loading and the possibility of achieving a quasi zero-order release for most drugs.Author: V Lenaerts, I Moussa, Y Dumoulin, F Mebsout, F Chouinard, P Szabo, M.A Mateescu, L Cartilier, R Marc...
https://www.sciencedirect.com/science/article/pii/S0168365997002563
Cross-linked high amylose starches have been developed as excipients for the formulation of controlled-release solid dosage forms for the oral delivery of drugs. Advantages of this new class of excipients include cost-effectiveness, readily accessible industrial manufacturing technology, high active ingredient core loading and the possibility of achieving a quasi zero-order release for most drugs.Author: V Lenaerts, I Moussa, Y Dumoulin, F Mebsout, F Chouinard, P Szabo, M.A Mateescu, L Cartilier, R Marc...
https://www.researchgate.net/file.PostFileLoader.html?id=5432a0d1d5a3f2a92f8b4669&assetKey=AS%3A271754100969484%401441802634898
Chapter 4 Contramid®: High-Amylose Starch for Controlled Drug Delivery François Ravenelle and Miloud Rahmouni Labopharm Inc., 480 Boulevard Armand-Frappier, Laval, Québec H7V 4B4, Canada
https://www.researchgate.net/publication/279418329_ContramidR_High-Amylose_Starch_for_Controlled_Drug_Delivery
Contramid®: High-Amylose Starch for Controlled Drug Delivery. Contramid® is a novel pharmaceutical excipient obtained by chemically and physically modifying a high-amylose corn starch. When a compressed tablet of Contramid® powder is placed in an aqueous medium, the material forms a hard gel displaying sponge-like viscoelastic properties.
https://www.sciencedirect.com/science/article/pii/S037851730900578X
Sodium carboxymethyl high amylose starch, CMHAS(Na), with a DS up to 1.74 were synthesized in non-aqueous medium (with yields as high as 72%) in order to investigate the influence of the degree of substitution (DS) on physical and drug release properties. The CMHAS(Na) was converted to protonated form, CMHAS(H), by acid treatment.Author: Marc Lemieux, Patrick Gosselin, Mircea Alexandru Mateescu
https://www.sciencedirect.com/science/article/pii/S0168365901004254
For cross-linked high amylose starch (HASCL) excipient (Contramid™), it was previously shown that orally administrable monolithic devices, with 20% loading for most drugs, are able to control the release over 18 to 24 h , .Author: Jérôme Mulhbacher, Pompilia Ispas-Szabo, Vincent Lenaerts, Mircea Alexandru Mateescu
https://www.sciencedirect.com/science/article/pii/S0144861718302819
Film-coated microparticles were developed for colon-specific drug delivery. • Starch-coated films showed improved acidic and enzymatic resistance in the GI tract. • Native and retrograded starches were used as binders to reinforce the resistance. • Suitable molecular mass and high crystallinity of starch are important factors.Author: Jin Chen, Jin Chen, Xiaoxi Li, Ling Chen, Fengwei Xie
https://www.researchgate.net/publication/333573876_Ampholytic_and_Polyelectrolytic_Starch_as_Matrices_for_Controlled_Drug_Delivery
Ampholytic and Polyelectrolytic Starch as Matrices for Controlled Drug Delivery Article (PDF Available) in Pharmaceutics 11(6):253 · June 2019 with 63 Reads How we measure 'reads'
http://pubs.acs.org/doi/abs/10.1021/bk-2006-0934.ch015
Contramid®: High-Amylose Starch for Controlled Drug Delivery Ravenelle and Rahmouni ACS Symposium Series , Volume 934 , pp 79–104
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