Hepatic Artery Drug Delivery

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Efficient Hepatic Delivery of Drugs: Novel Strategies and ...

    https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3826320/
    Oct 28, 2013 · These exciting evidences suggested that Lf-R might be a promising candidate for hepatocellular carcinoma targeting due to its high affinity for ASGP-R, and developing a hepatic carcinoma targeting drug delivery system employing the ASGP-R targeting ability of Lf-R is highly possible. Lacto Bionic Acid (LA) Ligand.Author: Nidhi Mishra, Narayan Prasad Yadav, Vineet Kumar Rai, Priyam Sinha, Kuldeep Singh Yadav, Sanyog Jain...

Hepatic arterial infusional chemotherapy in the management ...

    https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6095333/
    Colorectal liver metastases (CRLM) receive their blood supply predominantly through the hepatic artery. Intra-arterial drug delivery can optimize the dose and time exposure of chemotherapy to tumor cells while limiting systemic toxicity. Chemotherapy ...Author: Alexandre Doussot, Nancy E Kemeny, Michael I D'Angelica

Drug Infusion Systems - SynchroMed™ II Medtronic

    https://www.medtronic.com/us-en/healthcare-professionals/products/neurological/drug-infusion-systems/synchromed-ii.html
    Information for healthcare professionals about the SynchroMed™ II drug infusion pump used for Targeted Drug Delivery for the management of chronic pain. Close Cookie Statement. This site uses cookies to store information on your computer. Some are essential to make our site work; others help us improve the user experience.Phone: (800) 707-0933

STANDARDIZED PROCEDURE HEPATIC ARTERY INFUSION OF ...

    https://medicalaffairs.ucsf.edu/sites/g/files/tkssra856/f/wysiwyg/ahpPrivileges/Hepatic%20Arterial%20Infusion%20of%20Chemo%20(Adult,%20Peds).pdf
    HEPATIC ARTERY INFUSION OF CHEMOTHERAPY (Adults, Peds) 1 I. Definition Hepatic arterial infusion (HAI) of chemotherapy is accomplished by a small drug delivery system or pump that is implanted in a subcutaneous pocket in the lower abdomen. The pump reservoir stores and releases prescribed amounts of medicationFile Size: 23KB

Role of Hepatic Artery Infusion Chemotherapy in Treatment ...

    https://jamanetwork.com/journals/jamasurgery/fullarticle/2735967
    Aug 01, 2019 · Consequently, administration of chemotherapy into the hepatic artery allows selective drug delivery to the tumor(s) with relative sparing of normal parenchyma. 28 This anatomical phenomenon, along with pharmacologic factors discussed below, provides much of the rationale for liver-directed HAIC in the management of CRLM. Hepatic arterial ...Author: Jashodeep Datta, Raja R. Narayan, Nancy E. Kemeny, Michael I. D’Angelica

Arterial Chemotherapy Infusion & Chemoembolization of Liver

    https://www.medicinenet.com/chemo_infusion_and_chemoembolization_of_liver/article.htm
    The normal liver gets its blood supply from two sources: the portal vein (about 70%) and the hepatic artery (30%). Primary liver cancer, also known as hepatoma or hepatocellular carcinoma (HCC) gets its blood exclusively from the hepatic artery. These techniques can also be used to treat secondary, or metastatic liver cancer, which is cancer that spread to the liver from other primary sites.

Totally implanted drug delivery system for hepatic ...

    https://www.osti.gov/biblio/5527214
    Abstract. A totally implanted drug delivery system for hepatic arterial chemotherapy was evaluated in 13 patients with metastatic (11 colon and one carcinoid) or primary (one hepatoma) cancer of the liver.

The blooming intersection of transcatheter hepatic artery ...

    https://www.sciencedirect.com/science/article/pii/S1001841720301431
    2. Efficient drug delivery. Clinically, chemotherapeutic drugs are usually mixed directly with the embolization agent (e.g., lipiodol) to form an emulsion for TACE treatment.Although this method is straightforward and practical, the loaded drug is volatile in this state, and will be quickly eluted from the embolization agent following injection.Author: Hu Chen, Hongwei Cheng, Wenying Wu, Wenying Wu, Dengfeng Li, Jingsong Mao, Chengchao Chu, Gang Liu

Use of Lipiodol as a drug-delivery system for ...

    https://www.sciencedirect.com/science/article/pii/S1040842813001534
    Use of Lipiodol as a drug-delivery system for transcatheter arterial chemoembolization of hepatocellular carcinoma: A review. ... In vivo microscopy of the liver after injection of Lipiodol into the hepatic artery and portal vein in the rat. Acta Radiologica, 30 (1989), pp. 419-425.Author: Jean-Marc Idée, Boris Guiu

Hepatic arterial perfusion scintigraphy with Tc-99m-MAA ...

    https://pubs.rsna.org/doi/abs/10.1148/radiology.152.1.6233632
    Tc-99m-MAA hepatic arterial perfusion scintigraphy ( HAPS ) using a totally implanted drug delivery system was employed for hepatic arterial chemotherapy in 147 patients (335 studies). Complete per...Author: H. A. Ziessman, J. H. Thrall, P. J. Yang, S. C. Walker, E. A. Cozzi, J. E. Niederhuber, J. W. Gyves,...

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