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https://www.sciencedirect.com/science/article/pii/S0142961211007757
We developed a nanoparticulate drug delivery system decorated with AS1411 (Ap), a DNA aptamer specifically binding to nucleolin which was highly expressed in the plasma membrane of both cancer cells and endothelial cells in angiogenic blood vessels, as the targeting ligand to facilitate anti-glioma delivery of paclitaxel (PTX).Author: Jianwei Guo, Jianwei Guo, Xiaoling Gao, Lina Su, Lina Su, Huimin Xia, Guangzhi Gu, Zhiqing Pang, Xin...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7022905/
Dec 23, 2019 · These models can be key tools for the study of drug delivery to glioma cells across the BBB and the BBTB. Anticancer drugs are often tested in vivo using xenograft animals or genetically engineered murine models (reviewed in [235,355]). Xenograft models are obtained by injecting with primary tumor cells or immortalized cell lines either ...
https://www.ncbi.nlm.nih.gov/pubmed/21788069
We developed a nanoparticulate drug delivery system decorated with AS1411 (Ap), a DNA aptamer specifically binding to nucleolin which was highly expressed in the plasma membrane of both cancer cells and endothelial cells in angiogenic blood vessels, as the targeting ligand to facilitate anti-glioma delivery of paclitaxel (PTX).Author: Jianwei Guo, Jianwei Guo, Xiaoling Gao, Lina Su, Lina Su, Huimin Xia, Guangzhi Gu, Zhiqing Pang, Xin...
https://www.nature.com/articles/nnano.2017.54
Jun 19, 2017 · Cell-mediated drug-delivery systems have received considerable attention for their enhanced therapeutic specificity and efficacy in cancer treatment. Neutrophils (NEs), …Author: Jingwei Xue, Zekai Zhao, Lei Zhang, Lingjing Xue, Shiyang Shen, Yajing Wen, Zhuoyuan Wei, Lu Wang, L...
https://surgicalneurologyint.com/surgicalint-articles/convection-enhanced-drug-delivery-for-gliomas/
Convection-enhanced drug delivery for gliomas Andrew T. Healy , Michael A. Vogelbaum Neurosurgical Resident, Department of Neurological Surgery, Director, Center for Translational Therapeutics, Associate Director, Brain Tumor and Neuro-Oncology Center, ND40, Cleveland Clinic, 9500 Euclid Avenue, Cleveland, OH 44195, USA
https://www.thelancet.com/journals/lanonc/article/PIIS1470-2045(18)30322-X/fulltext
Direct drug delivery by way of convection-enhanced delivery has been hypothesised as an appealing therapeutic strategy for patients with diffuse intrinsic pontine glioma; however, early clinical experience with single case reports has been highly varied, precluding the drawing of meaningful conclusions.Author: Mark M Souweidane, Mark M Souweidane, Kim Kramer, Kim Kramer, Neeta Pandit-Taskar, Neeta Pandit-Task...
https://www.sciencedirect.com/science/article/pii/S0168365915301590
In recent decades, actively targeted drug delivery system has attracted extensive attention for effective delivery of chemotherapeutics to the tumor region, but there is still a long way to go. As an intracranial tumor, glioma possesses many distinctive characteristics from peripheral tumors.Author: Xiaoli Wei, Jie Gao, Changyou Zhan, Cao Xie, Zhilan Chai, Danni Ran, Man Ying, Ping Zheng, Weiyue Lu
https://www.mdpi.com/2079-4991/6/1/3/htm
This review will summarize recent progress on receptor-mediated drug delivery systems targeting to glioma, and conclude the challenges and prospects of receptor-mediated glioma-targeted therapy for future applications. Glioma has been considered to be the most frequent primary tumor within the central nervous system (CNS). The complexity of ...Author: Shanshan Wang, Ying Meng, Chengyi Li, Min Qian, Rongqin Huang
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