Gene Drug Delivery

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Drug and Gene Delivery Duke Biomedical Engineering

    https://bme.duke.edu/research/drug-gene-delivery
    Important areas in this growing field include development of delivery vehicles such as plasmids, nanoparticles, viruses, liposomes, peptide/protein complexes, and biomaterial scaffolds, as well as studies of drug and gene transport, delivery strategies, delivery barriers, and …

Genentech: Drug Delivery

    https://www.gene.com/stories/drug-delivery
    Jan 13, 2020 · Traditionally, drug delivery has focused on improving the performance of existing medicines, perhaps to extend their efficacy or reduce side effects. Even though these improvements have been very successful, delivery has often been more of an afterthought in the development process.

Novel gene delivery systems - PubMed Central (PMC)

    https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3687232/
    Nov 27, 2012 · An ideal nonviral gene carrying system should possess all these merits without any compromise to its gene transferring efficiency. The viral gene delivery systems include lytic and nonlytic vectors for drug delivery. Inspite of its toxicity they are still preferred because of their long term expression, stability, and integrity.

Drug Delivery Systems - nibib.nih.gov

    https://www.nibib.nih.gov/science-education/science-topics/drug-delivery-systems-getting-drugs-their-targets-controlled-manner
    Drug delivery systems are engineered technologies for the targeted delivery and/or controlled release of therapeutic agents. Drugs have long been used to improve health and extend lives. The practice of drug delivery has changed dramatically in the past few decades and even greater changes are …

Viral and nonviral delivery systems for gene delivery

    https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3507026/
    Jul 06, 2012 · INTRODUCTION. Basically gene therapy is an intracellular delivery of genomic materials (transgene) into specific cells to generate a therapeutic effect by correcting an existing abnormality or providing the cells with a new function.[] Different types of gene delivery systems may be applied in gene therapy to restore a specific gene function or turning off a special gene(s).

BMED 4450 - Drug and Gene Delivery - Acalog ACMS™

    http://catalog.rpi.edu/preview_course_nopop.php?catoid=12&coid=21958
    The course presents several aspects of drug and gene delivery including: 1) definitions of what drugs or gene are; 2) pharmacokinetics and pharmacodynamics; 3) biomaterial selection considerations; 4) bioactivity considerations;; 5) physiological and biochemical barriers to drug delivery; 6) diffusion controlled, dissolution controlled, and osmotic controlled drug delivery systems; 7 ...

Drug-delivery technology leads to sustained HIV antibody ...

    https://www.nih.gov/news-events/news-releases/drug-delivery-technology-leads-sustained-hiv-antibody-production-nih-study
    Mar 09, 2020 · This drug-delivery technology uses a harmless virus to deliver an antibody gene into human cells, enabling the body to generate the antibody over an extended time. With further development, such a strategy could be applied to prevent and treat a wide variety of infectious diseases, according to the study investigators.

GDD NIH Center for Scientific Review

    https://public.csr.nih.gov/StudySections/DBIB/BST/GDD
    The Gene and Drug Delivery Systems (GDD) study section considers grant applications focused on fundamental aspects of gene and drug delivery, including delivery vehicle development, targeting strategies, and biological barriers. Applications are typically focused on bioengineering principles and may not be hypothesis driven.

Drug and Gene Delivery University of Virginia School of ...

    https://engineering.virginia.edu/departments/biomedical-engineering/research/drug-and-gene-delivery
    Drug and Gene Delivery. UVA is widely recognized for its strengths in biopanning for novel peptide ligands in vivo, as well as using peptides and antibodies to target the delivery of microbubbles, liposomes and genes in the settings of cancer, cardiovascular and infectious disease.

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