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https://www.sciencedirect.com/science/article/pii/S0168365910009168
Gene delivery with bisphosphonate-stabilized calcium phosphate nanoparticles. ... Calcium phosphate-DNA co-precipitates have been used for gene delivery for more than 35 years and have the advantage of being nontoxic, easy to produce, and having the ability to complex nucleic acids leading to efficient transfection. ... A. Kovtun, R. Heumann, M ...Author: Elisabeth V. Giger, Josep Puigmartí-Luis, Rahel Schlatter, Bastien Castagner, Petra S. Dittrich, Jea...
https://www.sciencedirect.com/science/article/abs/pii/S0168365910009168
Gene delivery with bisphosphonate-stabilized calcium phosphate nanoparticles ... The entrapment of genetic material into nanoparticles constitutes a promising approach to increase the in vitro and in vivo transfection activity. Calcium phosphate-DNA co-precipitates have been used for gene delivery for more than 35 years and have the advantage ...
https://www.researchgate.net/publication/49638915_Gene_delivery_with_bisphosphonate-stabilized_calcium_phosphate_nanoparticles
Gene delivery with bisphosphonate-stabilized calcium phosphate nanoparticles Article in Journal of Controlled Release 150(1):87-93 · November 2010 with 36 Reads How we measure 'reads'
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6781291/
Sep 11, 2019 · 1. Introduction. Over the past several decades, gene therapy has become one of the most actively developing and promising branches of medicine [1,2,3,4,5].Calcium phosphate (CaP) nanoparticles, as a promising vehicle for gene delivery, have been widely used because of their biocompatibility, biodegradability and adsorptive capacity for nucleic acids [6,7].Author: Ming Zhao, Ji Li, Dawei Chen, Haiyang Hu
https://www.research-collection.ethz.ch/handle/20.500.11850/33387
Upper Right Menu. Login. HelpAuthor: Elisabeth V. Giger, Josep Puigmartí-Luis, Rahel Schlatter, Bastien Castagner, Petra S. Dittrich, Jea...
https://pubs.acs.org/doi/10.1021/acsabm.9b00994
Calcium phosphate (CP) nanoparticles (NPs) have been used in various applications for delivery of nucleic acid (NA) cargos with ideal biocompatibility and safety. However, some critical issues such as poor stability and aggregation in water solution hinder the industrial application of CP NPs. To further utilize CP NPs for NA delivery, this study specifically focused on the modification of CP ...Author: Bing Sun, Marianne Gillard, Yanheng Wu, Peihong Wu, Zhi Ping Xu, Wenyi Gu
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6044815/
May 31, 2017 · It is well known that calcium phosphate (CaP) nanoparticles are promising nonviral inorganic vectors for gene delivery due to their capacity of transfection of various mammalian cells in vitro, as well as low immune responses and cytotoxicity. 18−20 The calcium phosphonates can be regarded as organic-functionalized CaP, wherein the special ...Author: Xiaona Wei, Xiaodan Liu, Xue Wang, Yuanyuan Bao, Xin Shi, Liwei Sun
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