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https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2835126/
Apr 30, 2009 · Gene therapy covers a broad spectrum of applications, from gene replacement and knockdown for genetic or acquired diseases such as cancer, to vaccination, each with different requirements for gene delivery. Viral vectors and synthetic liposomes have emerged ...Author: Yiqi Seow, Matthew J Wood
https://www.ncbi.nlm.nih.gov/pubmed/17406299
Construction of diverse adeno-associated viral libraries for directed evolution of enhanced gene delivery vehicles. Koerber JT(1), Maheshri N, Kaspar BK, Schaffer DV. Author information: (1)Department of Chemical Engineering and the Helen Wills Neuroscience Institute, University of California, Berkeley, California 94720-1462, USA.Author: James T Koerber, Narendra Maheshri, Brian K Kaspar, David V Schaffer
https://www.nejm.org/doi/full/10.1056/NEJM199605023341809
For gene therapy to realize its clinical potential, there must be efficient and safe strategies of delivering therapeutic genes to somatic cells in vivo. Perhaps this problem simply represents a sp...Author: James M. Wilson
https://www.sciencedirect.com/science/article/pii/S0024320520302988
The development of efficient non-toxic gene delivery vehicles and strategies that can carry and deliver foreign DNA to specific cell types is the ultimate goal in gene therapy. Using recombinant bacteria and virus have shown to be promising and currently being broadly investigated.Author: Balamurugan Shanmugaraj, Lohanathan Bharathi Priya, B. Mahalakshmi, Shanmugam Subbiah, Rouh-Mei Hu, ...
https://www.sciencedirect.com/science/article/pii/S0378517319308476
As a model system for gene delivery, the yields of EV production from parental sources and the selectivity to the cells of interest need to be considered. Our data demonstrated A549 cells had a 2.4-fold higher (***p < 0.001) production yield of EVs compared to the EV yields of 3 T3 cells.Author: Yong-Yu Jhan, Daniel Prasca-Chamorro, Guillermo Palou Zuniga, David Mitchell Moore, Shreedevi Arun K...
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