Gene Delivery Tissue Engineering

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Gene Delivery for Tissue Engineering - ScienceDirect

    https://www.sciencedirect.com/journal/advanced-drug-delivery-reviews/vol/58/issue/4
    Gene delivery for tissue engineering. W.T. Godbey, A.G. Mikos. Pages 465-466 Download PDF; select article Current status of polymeric gene delivery systems. ... Natural polymers for gene delivery and tissue engineering. Jiyoung M. Dang, Kam W. Leong. Pages 487-499 Download PDF. Article preview.

Tissue engineering by modulated gene delivery - ScienceDirect

    https://www.sciencedirect.com/science/article/pii/S0169409X06000548
    In this paper, some DDS technology and methodology to enhance the in vivo therapeutic efficiency of gene are overviewed, while several concrete examples are introduced to emphasize importance of genetic approaches in tissue engineering. 2. Approaches for modulated non-viral gene delivery systems 2.1. Physical stimuliAuthor: Masaya Yamamoto, Masaya Yamamoto, Yasuhiko Tabata

Gene Delivery in Bone Tissue Engineering: Progress and ...

    https://www.liebertpub.com/doi/10.1089/107632704322791934
    Gene therapy used for tissue engineering applications 18 February 2010 Journal of Pharmacy and Pharmacology, Vol. 59, No. 3 Treatment of osteonecrosis of the femoral head with hBMP-2-gene-modified tissue-engineered bone in goatsAuthor: Kris A. Partridge, Richard O.C. Oreffo

Gene delivery in tissue engineering and regenerative ...

    https://www.researchgate.net/publication/270280127_Gene_delivery_in_tissue_engineering_and_regenerative_medicine_Gene_Delivery_in_Tissue_Engineering_and_Regenerative_Medicine
    Gene delivery/therapy is also discussed as a forefront area that represents another cross point between tissue engineering and pharmaceutical biotechnology, in which nucleic acids can be ...

Gene delivery from polymer scaffolds for tissue engineering

    https://www.tandfonline.com/doi/abs/10.1586/17434440.1.1.127
    Jul 12, 2017 · Gene delivery is a versatile approach, capable of targeting any cellular process through localized expression of tissue inductive factors. The design and application of tissue engineering scaffolds for localized gene transfer are reviewed.Author: Jae Hyung Jang, Tiffany L. Houchin, Lonnie D. Shea

Physical non-viral gene delivery methods for tissue ...

    https://www.ncbi.nlm.nih.gov/pubmed/23099792
    The integration of gene therapy into tissue engineering to control differentiation and direct tissue formation is not a new concept; however, successful delivery of nucleic acids into primary cells, progenitor cells, and stem cells has proven exceptionally challenging.Author: Adam Joseph Mellott, M. Laird Forrest, Michael S. Detamore

In situ bone tissue engineering via ultrasound-mediated ...

    https://stm.sciencemag.org/content/9/390/eaal3128.full
    May 17, 2017 · Here, we used ultrasound-mediated, microbubble-enhanced gene delivery for in situ bone engineering in a mini-pig model of tibial fracture repair. We showed that ultrasound-mediated BMP-6 delivery to cells residing within the fracture site achieved transient local gene expression, mainly targeting endogenous MSCs. Osteogenic gene delivery resulted in a spatial and temporal expression pattern that is consistent with nonviral gene delivery …Author: Maxim Bez, Maxim Bez, Dmitriy Sheyn, Wafa Tawackoli, Pablo Avalos, Galina Shapiro, Joseph C. Giaconi...

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