Gene Delivery Systems Recent Progress In Viral And Non-Viral Therapy

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Gene Delivery Systems: Recent Progress in Viral and Non ...

    https://www.intechopen.com/books/recent-advances-in-novel-drug-carrier-systems/gene-delivery-systems-recent-progress-in-viral-and-non-viral-therapy
    The use of non-viral gene delivery systems in gene therapy also significantly increased in recent years. Naked plasmid DNA, coated with gold particles was effectively introduced to cells using the non-viral gene gun technique. This technique was first used in plant cells in 1987, and is today commonly used in mammal cells and tissues.Author: Erdal Cevher, Ali Demir Sezer, Emre Şefik Çağlar

Gene Delivery Systems: Recent Progress in Viral and Non ...

    https://cdn.intechopen.com/pdfs/40265/InTech-Gene_delivery_systems_recent_progress_in_viral_and_non_viral_therapy.pdf
    Gene Delivery Systems: Recent Progress in Viral and Non-Viral Therapy 439 development of retroviral vectors (Yaron et al., 1997). In the mid-1980s, gene transfer to mammalian cells became a routine procedure. Retrovirus-based gene therapies brought significant advantages, as they can stably integrate their genomes to host-cell chromosomes.

(PDF) Gene Delivery Systems: Recent Progress in Viral and ...

    https://www.researchgate.net/publication/257924981_Gene_Delivery_Systems_Recent_Progress_in_Viral_and_Non-Viral_Therapy
    Gene Delivery Systems: Recent Progress in Viral and Non-Viral Therapy 461 Transformation of a normal cell to a neoplastic cell occurs by multi-mutationary changes of the cells at the genetic level.

Nonviral Gene Delivery: Principle, Limitations, and Recent ...

    https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2782077/
    Oct 16, 2009 · Gene transfer of anticancer therapeutic genes, either with tumor-suppresser or enzyme-directed prodrug or by siRNA-based gene knockdown approaches, has been explored as a possible therapeutic intervention for cancer gene therapy.Author: Mohammed S. Al-Dosari, Xiang Gao

Viral and nonviral delivery systems for gene delivery

    https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3507026/
    Jul 06, 2012 · Although numerous viral and nonviral gene delivery systems have been developed in the last 3 decades, no delivery system has been designed that can be applied in gene therapy of all kinds of cell types in vitro and in vivo with no limitation and side effects.

Viral Vector Systems for Gene Therapy: A Comprehensive ...

    https://journals.sagepub.com/doi/full/10.1177/1535676019899502
    Applications of viral vectors and nonviral gene delivery systems have found an encouraging new beginning in gene therapy in recent years. Although several viral vectors and nonviral gene delivery systems have been developed in the past 3 decades, no one delivery system can be applied in gene therapy to all cell types in vitro and in vivo.Author: Sumit Ghosh, Alex M. Brown, Chris Jenkins, Katie Campbell

Non viral vectors in gene therapy- an overview. - Abstract ...

    https://www.europepmc.org/articles/PMC4347098/
    Europe PMC is an archive of life sciences journal literature. Find the latest peer-reviewed research articles and preprints on Coronavirus here.Author: Murali Ramamoorth, Aparna Narvekar

Non-Viral Delivery Systems in Gene Therapy IntechOpen

    https://www.intechopen.com/books/gene-therapy-tools-and-potential-applications/non-viral-delivery-systems-in-gene-therapy
    Gene delivery systems include viral vectors and non-viral vectors. Viral vectors are the most effective, but their application is limited by their immunogenicity, oncogenicity and the small size of the DNA they can transport. Non-viral vectors are safer, of …Author: Alicia Rodríguez Gascón, Ana del Pozo-Rodríguez, María Ángeles Solinís

Non-viral gene therapy: Gains and challenges of non ...

    https://www.sciencedirect.com/science/article/pii/S0168365915302649
    Non-viral site-specific gene therapy via phage ФC31-derived integrase system: The phage ФC31 integrase-mediated site-specific integration technology is applied as a DNA vector system for non-viral delivery and insertion of therapeutic gene of interest (GOI) from a donor DNA vector into the specific sites distributed in the recipient cell genome.Author: Marianna Foldvari, Ding Wen Chen, Nafiseh Nafissi, Daniella Calderon, Lokesh Narsineni, Amirreza Raf...

Gene delivery system - SlideShare

    https://www.slideshare.net/Aparajitha_Anne/gene-delivery-system
    May 19, 2012 · Inorganic Nanoparticles:It one of the non-viral gene delivery system where we use gold .silicaand iron oxide and calcium phosphate some of the benefits are storagestability, low manufacturing cost and often time, low immunogenicity.

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