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https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5449975/
Apr 28, 2017 · Regardless of the vector, there are two main approaches to affecting the genetics of targeted cells: (1) Gene therapy where DNA is delivered with the aim of providing a functional copy of a defective gene in the patient, and (2) The delivery of therapeutic nucleic acids which include microRNA (miRNA), short hairpin RNA (shRNA), antisense oligonucleotides (AONS) and small interfering RNA …Author: Michael K. Riley, Wilfred Vermerris
https://www.sciencedirect.com/topics/neuroscience/gene-delivery
9.7.4 Gene delivery. Gene delivery is a versatile approach, capable of targeting any cellular process through localized expression of tissue inductive factors. Introduction of the gene rather than a product such as a growth factor is thought to be cheaper and more efficient for treating non-healing wounds.
https://www.thermofisher.com/us/en/home/life-science/cell-culture/transfection/transfection-support/gene-delivery-selection-guide.html
Researchers have a wide variety of gene delivery techniques to introduce plasmid DNA, siRNA or duplex RNAi, oligonucleotides, and RNA into eukaryotic cells for a variety of research and drug discovery applications. A review of these techniques is provided on the table below.
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6417261/
Mar 12, 2019 · The non-viral gene delivery systems have also treated for the physicochemical approaches such as physical method and chemical method. Several kinds of gene delivery systems have discussed on the gene delivery systems of cationic biomedical polymers such as polysaccharides, polyethylenimine (PEI), and poly(L-lysine)(PLL) derivatives.Author: YK Sung, SW Kim
https://www.tandfonline.com/doi/figure/10.1080/14712598.2018.1416089?scroll=top&needAccess=true
(2018). AAV gene delivery to the spinal cord: serotypes, methods, candidate diseases, and clinical trials. Expert Opinion on Biological Therapy: Vol. 18, No. 3, pp ...
https://www.nature.com/articles/s41570-018-0039-1
Sep 21, 2018 · Chemistry has a key role in the development of innovative synthetic materials to overcome the challenges of producing next-generation gene delivery therapies and protocols. In this Review, we discuss the latest chemical advances in the production of materials for the delivery of nucleic acids to cells and for gene therapy.Author: Irene Lostalé-Seijo, Javier Montenegro
https://www.sciencedirect.com/science/article/pii/S0001868618303865
Various methods have been developed to improve the properties of chitosan related to gene delivery. This review introduces the features of chitosan in gene delivery, summarizes current progress toward methods promoting the properties of chitosan related to gene delivery, and presents different applications of chitosan in gene delivery vectors.Author: Di Chuan, Tao Jin, Rangrang Fan, Liangxue Zhou, Gang Guo
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