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https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3507026/
Jul 06, 2012 · INTRODUCTION. Basically gene therapy is an intracellular delivery of genomic materials (transgene) into specific cells to generate a therapeutic effect by correcting an existing abnormality or providing the cells with a new function.[] Different types of gene delivery systems may be applied in gene therapy to restore a specific gene function or turning off a special gene(s).
https://www.hindawi.com/journals/bmri/2015/932161/
The method of choice for introducing transgenes into plants depends on the expression vector and the host plants. These methods include direct delivery by gene gun and indirect delivery through using Agrobacterium tumefaciens or plant viruses . 2.1. Direct Delivery MethodsAuthor: Qiang Chen, Huafang Lai
https://www.thermofisher.com/us/en/home/references/gibco-cell-culture-basics/transfection-basics/gene-delivery-technologies.html
Gene delivery technologies Transfection technologies available today can be broadly classified into three groups: chemical, biological, and physical. No one method can be applied to all cells and all experiments.
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4313362/
In this study, we describe an optimized method for gene delivery into embryonic DRG neurons, with high transfection efficiency of >60%, and low cytotoxicity as reflected in a 2/3 survival rate and robust differentiation, comparable to non-transfected cultures. Primary neurons present a particular challenge to successful gene transfer.Author: Lingli Yu, Lingli Yu, Florie Reynaud, Julien Falk, Ambre Spencer, Ambre Spencer, Yin-Di Ding, Yin-Di...
https://www.technologyreview.com/s/608898/five-ways-to-get-crispr-into-the-body/
Sep 22, 2017 · Five Ways to Get CRISPR into the Body Scientists are investigating a range of different delivery mechanisms for the gene-editing tool, from topical gels to skin grafts. by Emily Mullin
https://engene.com/science/
Jul 10, 2017 · The delivered sequences can encode proteins, peptides, antibodies, and the like. Importantly, we have formulated our proprietary DNA delivery system into a Gene Pill™ to provide oral delivery of therapeutic genes to the gut – a game-changing technology that enables oral delivery of protein therapeutics.
https://www.liebertpub.com/doi/10.1089/hum.2019.127
Dec 16, 2019 · There are many kidney diseases that might be addressed by gene therapy. However, gene delivery to kidney cells is inefficient. This is due, in part, to the fact that the kidney excludes molecules above 50 kDa and that most gene delivery vectors are megaDaltons in mass.Author: Jeffrey D. Rubin, Tien V. Nguyen, Kari L. Allen, Katayoun Ayasoufi, Michael A. Barry
https://systembio.com/applications/gene-delivery/
Exosome Engineering—use exosomes as a non-viral method for gene delivery; Syn2Clone Custom Constructs—keep your hands off your pipettes with this service where you simply email us your gene sequence. We synthesize the gene and clone it into the SBI construct of your choice, all for little more than the cost of the empty vector.
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