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https://www.researchgate.net/publication/8689436_Gene_delivery_by_lentivirus_vectors_an_overview
Gene delivery by lentivirus vectors an overview Article · Literature Review in Methods in Molecular Biology 246:367-90 · January 2004 with 72 Reads How we measure 'reads'Author: Tal Kafri
https://link.springer.com/article/10.1007/s12033-007-0010-8
Apr 17, 2007 · The capacity to efficiently transduce nondividing cells, shuttle large genetic payloads, and maintain stable long-term transgene expression are attributes that have brought lentiviral vectors to the forefront of gene delivery vehicles for research and therapeutic applications in a clinical setting. Our discussion initiates with advances in lentiviral vector development and how these ...Author: Adam S. Cockrell, Tal Kafri
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3507026/
Jul 06, 2012 · INTRODUCTION. Basically gene therapy is an intracellular delivery of genomic materials (transgene) into specific cells to generate a therapeutic effect by correcting an existing abnormality or providing the cells with a new function.[] Different types of gene delivery systems may be applied in gene therapy to restore a specific gene function or turning off a special gene(s).
https://www.sciencedirect.com/topics/biochemistry-genetics-and-molecular-biology/lentivirus-vector
Lentivirus Vector. Lentiviral vectors are a preferred platform for anti-HIV gene therapeutics, due to their ability to pass through the nuclear envelope into cell nucleus thereby allowing transduction of nondividing cells and to maintain long-term and sustained expression of the genes carried by the vector.
https://link.springer.com/protocol/10.1385%2F1-59259-650-9%3A367
An, D.S., Chen, I. S., and Wersto, R. P. (2001) Fibronectin fragment CH-296 inhibits apoptosis and enhances ex vivo gene transfer by murine retrovirus and human lentivirus vectors independent of viral tropism in nonhuman primate CD34(+) cells.Author: Adam S. Cockrell, Tal Kafri
https://www.ncbi.nlm.nih.gov/pubmed/17873406
1. Mol Biotechnol. 2007 Jul;36(3):184-204. Gene delivery by lentivirus vectors. Cockrell AS(1), Kafri T. Author information: (1)Gene Therapy Center, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599, USA. The capacity to efficiently transduce nondividing cells, shuttle large genetic payloads, and maintain stable long-term transgene expression are attributes that have brought ...Author: Adam S. Cockrell, Tal Kafri
https://www.takarabio.com/learning-centers/gene-function/viral-transduction/recombinant-virus-comparison
However, selecting the best viral gene delivery system for your experimental aim can be challenging. Use the tables below to compare the characteristics of lentivirus, retrovirus, adenovirus, and adeno-associated virus (AAV), and select the best viral transduction system for your experiment.
https://www.addgene.org/viral-vectors/
Overview of Viral Plasmids. While plasmids are typically used to encode, propagate, and manipulate genetic information, viruses are a powerful tool for the delivery of this genetic information to cells. Adapting plasmid DNA for use with virus-mediated delivery has many advantages for research.
https://www.sciencedirect.com/topics/agricultural-and-biological-sciences/lentivirus
Current recombinant lentivectors are derived from human immunodeficiency virus (HIV) and other nonhuman lentivirus, such as feline immunodeficiency virus (FIV) and equine infectious anemia virus (EIAV). The potential use of lentivirus in human gene therapy has led to major advances in improving the safety of these vectors.
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