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https://www.ncbi.nlm.nih.gov/pubmed/17873406
The capacity to efficiently transduce nondividing cells, shuttle large genetic payloads, and maintain stable long-term transgene expression are attributes that have brought lentiviral vectors to the forefront of gene delivery vehicles for research and therapeutic applications in a clinical setting.Author: Adam S. Cockrell, Tal Kafri
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2862356/
Aug 15, 2006 · Gene Delivery to the Spinal Cord: Comparison Between Lentiviral, Adenoviral, and Retroviral Vector Delivery Systems ... Viral gene delivery for spinal cord injury (SCI) is a promising approach for enhancing axonal regeneration and neuroprotection. ... lentiviral-mediated gene delivery is best suited for situations when long-term delivery of a ...Author: Ahmed A. Abdellatif, Jennifer L. Pelt, Richard L. Benton, Russell M. Howard, Pantelis Tsoulfas, Peip...
https://www.labome.com/method/Nucleic-Acid-Delivery-Lentiviral-and-Retroviral-Vectors.html
Lentiviral and retroviral gene delivery systems exploit aspects of retrovirus replication to provide stable integration of the desired nucleic acid sequence. Whereas transfection of nucleic acids results only in transient transgene expression, the activity of the viral integrase in retroviral and lentiviral-based systems allows for stable ...Author: Erin P O’Keefe
https://www.thermofisher.com/uk/en/home/technical-resources/technical-reference-library/protein-expression-support-center/lentiviral-gene-delivery-support/lentiviral-gene-delivery-support-getting-started.html
Find answers to commonly asked questions related to lentiviral gene delivery for mammalian expression, ranging from biosafety features to setting up of the experiment for cloning, lentivirus production, storage of lentiviral stocks, viral titering, transduction, and analysis of expression.
https://www.liebertpub.com/doi/10.1089/hum.2019.127
Dec 16, 2019 · Comparison of Gene Delivery to the Kidney by Adenovirus, Adeno-Associated Virus, and Lentiviral Vectors After Intravenous and Direct Kidney Injections Jeffrey D. Rubin Tien V. NguyenAuthor: Jeffrey D. Rubin, Tien V. Nguyen, Kari L. Allen, Katayoun Ayasoufi, Michael A. Barry
https://www.nature.com/articles/s41375-018-0106-0
Mar 22, 2018 · In vivo gene delivery using a lentiviral vector has also been applied clinically to the eye . These approaches face a number of hurdles including efficiency, need for tissue-restricted promoters ...Author: Michael C. Milone, Una O’Doherty
https://www.thermofisher.com/us/en/home/technical-resources/technical-reference-library/protein-expression-support-center/lentiviral-gene-delivery-support/lentiviral-gene-delivery-support-troubleshooting.html
View our FAQs for troubleshooting your lentiviral gene delivery experiment and find solutions to problems ranging from low viral titer to poor expression.
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