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https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3299903/
The purpose of this paper is to describe a) the relationship between oxidative stress and mitochondrial dysfunction and the pathological role of mitochondria in Alzheimer’s disease and diabetes, b) barriers for drug delivery to the mitochondria, and c) functionalized and non-functionalized nanosystems for mitochondrial drug delivery. The ...Author: Shelley A. Durazo, Uday B. Kompella
https://www.researchgate.net/publication/51850683_Functionalized_Nanosystems_for_Targeted_Mitochondrial_Delivery
Mitochondrial-targeted drug delivery mediated by nanosystems, such as nanoparticles and liposomes, can result in a substantially increase in the therapeutic efficacy with a drastic reduction in ...
https://www.sciencedirect.com/science/article/pii/S1567724911003175
The purpose of this paper is to describe a) the relationship between oxidative stress and mitochondrial dysfunction and the pathological role of mitochondria in Alzheimer's disease and diabetes, b) barriers for drug delivery to the mitochondria, and c) functionalized and non-functionalized nanosystems for mitochondrial drug delivery. The ...Author: Shelley A. Durazo, Uday B. Kompella
https://www.ncbi.nlm.nih.gov/pubmed/22138492
Functionalized nanosystems for targeted mitochondrial delivery. Durazo SA(1), Kompella UB. Author information: (1)Nanomedicine and Drug Delivery Laboratory, Department of Pharmaceutical Sciences, University of Colorado Anschutz Medical Campus, Aurora, CO 80045, USA.Author: Shelley A. Durazo, Uday B. Kompella
https://www.sciencedirect.com/science/article/pii/B9780128177761000055
The vesicle formation of dequalinium chloride (DQA) was discovered by Prof. Volkmar Weissig in 1998, and was the first mitochondria-targeted nano carrier , .DQAsomes were reported for mitochondrial targeting vectors to be used as gene-delivery systems , .Dequalinium (1,1′-decamethylene bis-4-aminoquinaldinium chloride; DQA) is a cationic bola amphiphilic compound composed of two …Author: Saravana Babu Chidambaram, Bipul Ray, Abid Bhat, Arehally Marappa Mahalakshmi, Tuladhar Sunanda, Pad...
https://www.researchgate.net/publication/278681699_Targeted_Drug_Delivery_to_the_Mitochondria
Request PDF Targeted Drug Delivery to the Mitochondria Mitochondria are of an increasing interest in pharmaceutical and medical research since it has emerged as an intriguing target for ...
https://link.springer.com/chapter/10.1007%2F978-3-319-11355-5_7
Nov 05, 2014 · This chapter deals with different aspects of mitochondrial drug delivery, current strategies of mitochondrial targeting and their possible therapeutic applications. ... (2012) Functionalized nanosystems for targeted mitochondrial delivery. ... Targeted Drug Delivery to the Mitochondria. In: Devarajan P., Jain S. (eds) Targeted Drug Delivery ...Author: Udita Agrawal, Rajeev Sharma, Suresh P. Vyas
https://pubs.acs.org/doi/full/10.1021/nl801908y
Jul 09, 2008 · Organelle-Targeted Nanocarriers: Specific Delivery of Liposomal Ceramide to Mitochondria Enhances Its Cytotoxicity in Vitro and in Vivo ... Mitochondrial Delivery of Doxorubicin by Triphenylphosphonium-Functionalized Hyperbranched Nanocarriers Results in Rapid and Severe Cytotoxicity. ... Functionalized nanosystems for targeted mitochondrial ...Author: Sarathi V. Boddapati, Gerard G. M. D’Souza, Suna Erdogan, Vladimir P. Torchilin, Volkmar Weissig
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