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http://www.eurekaselect.com/99022/article
All the examples show that these functionalized mesoporous silica-based systems have great potential for a variety of drug delivery applications, specifically in the fields of the drug targeted and controlled delivery systems.
https://www.sciencedirect.com/science/article/pii/S1044579X1930104X
In this context, mesoporous silica nanoparticles (MSNPs) with structural size < 500 nm offers exceptional qualities for multipurpose drug delivery applications. MSNPs include a bunch of tiny hollow nanocapsular structures and provide opportunity for conjugation of drug molecules and/or therapeutic agents through the open functional groups.Author: Abul Barkat, Sarwar Beg, Sunil K Panda, Khalid S Alharbi, Mahfoozur Rahman, Farhan J Ahmed
https://pubs.rsc.org/en/content/articlelanding/2012/cs/c2cs15308d
In the past decade, non-invasive and biocompatible mesoporous silica materials as efficient drug delivery systems have attracted special attention. Great progress in structure control and functionalization (magnetism and luminescence) design has been achieved for biotechnological and biomedical applications.Author: Piaoping Yang, Piaoping Yang, Shili Gai, Jun Lin
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4522861/
Mesoporous silica nanoparticles due to their low toxicity and high drug loading capacity, so they are used in controlled and target drug delivery system. Basically, silica is widely present in the environment in comparison to other metal oxides like titanium and iron oxides it has comparatively better biocompatibility. The mesoporous form of silica has unique properties, particularly in loading of …
https://www.sciencedirect.com/science/article/pii/S1549963414005462
From the Clinical Editor. This comprehensive review presents recent advances in mesoporous silica nanoparticles assisted drug delivery systems, including both immediate and sustained delivery systems as well as controlled release and targeted drug delivery systems.Author: Ying Wang, Qinfu Zhao, Ning Han, Ling Bai, Jia Li, Jia Liu, Erxi Che, Liang Hu, Qiang Zhang, Tongyin...
https://pubs.acs.org/doi/abs/10.1021/la500746e
The synthesis of a series of β-cyclodextrin modified mesoporous silica nanoparticles with hydroxyl, amino, and thiol groups was described. A comparison of their mucoadhesive properties and potential as a drug delivery system for superficial bladder cancer therapy was made. The thiol-functionalized nanoparticles exhibit significantly higher mucoadhesivity on the urothelium as compared to the ...Author: Quan Zhang, Koon Gee Neoh, Liqun Xu, Shengjie Lu, En Tang Kang, Ratha Mahendran, Edmund Chiong
https://www.hindawi.com/journals/jnm/2017/2069685/
The MSNs were prepared using ethanol and water as the reaction medium and CTAB as a surfactant, according to previous reports [31]. Briefly, 0.5 g of CTAB was added to an emulsion system composed of 0.8 ml of aqueous ammonia, 20 ml of ethanol, and 70 ml of H 2O.Author: Xiaoyan Xu, Chao Wu, Andi Bai, Xuan Liu, Huiling Lv, Ying Liu
https://www.researchgate.net/publication/280868053_Mesoporous-Silica-Functionalized_Nanoparticles_for_Drug_Delivery
Therefore, mesoporous silica particles enable the development of carrier systems, which combine targeting moieties, Tc-and Re-based imaging functions (radio-or UV-labels), and drug loading in a...
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