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https://journal.pda.org/content/67/3/214
May 01, 2013 · The objective of this work was to develop and evaluate a floating–pulsatile drug delivery of atenolol. The floating–pulsatile concept was applied to increase the gastric residence of the dosage form by having lag phase followed by a burst release. The system was generated which consisted of three different parts: a core tablet, containing the active ingredient; an erodible outer …Author: Swati C. Jagdale, Monali S. Sali, Ajay L. Barhate, Bhanudas S. Kuchekar, Aniruddha R. Chabukswar
http://impactfactor.org/PDF/IJDDT/7/IJDDT,Vol7,Issue4,Article2.pdf
pulsatile dosage form, in which the drug is released rapidly in a time-controlled fashion after rupturing of the pulsatile coating. Objective of this present investigation was to develop and evaluate a floating- pulsatile drug delivery system. The system consists of three different parts, a core tablet,
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4065132/
Apr 14, 2014 · Lisinopril is an angiotensin-converting enzyme (ACE) inhibitor, primarily used for the treatment of hypertension, congestive heart failure, and heart attack. It belongs to BCS class III having a half-life of 12 hrs and 25% bioavailability. The purpose of the present work was to develop a press-coated, floating-pulsatile drug delivery system.
https://www.researchgate.net/publication/331373596_Development_and_Evaluation_of_Floating_Pulsatile_Drug_Delivery_System_of_Meloxicam
Apr 02, 2018 · The main objective of the present research work was to develop chronomodulated, floating-pulsatile drug delivery system to release the drug in distal small intestine part of the GIT in …
https://www.scholarsresearchlibrary.com/articles/formulation-and-evaluation-of-floating-pulsatile-drug-delivery-system-of-metoprolol-tartrate.pdf
The floating pulsatile drug delivery system was designed such that rapid release core tablet of MT was dry coated by the layer of HPMC to impart pulsatile release characteristics and the top cover buoyant layer ensured the floating of the system (figure 1). Developed formulations wereAuthor: Anuradha K. Salunkhe, Remeth J. Dias, Kailas K. Mali, Niranjan S. Mahajan, Vishwajeet S. Ghorpade
https://www.academia.edu/26741260/Formulation_Development_and_Evaluation_of_Floating_Pulsatile_Drug_Delivery_System_of_Atenolol
Formulation, Development, and Evaluation of Floating Pulsatile Drug Delivery System of Atenolol
https://www.researchgate.net/publication/276247409_Formulation_and_evaluation_of_floating_pulsatile_drug_delivery_system_of_Metoprolol_tartrate
The main objective of the present study was to develop a multiple-unit, floating-pulsatile drug delivery system for obtaining no drug release during floating and in the proximal small intestine ...
https://www.academia.edu/32613713/FORMULATION_AND_EVALUATION_OF_FLOATING-_PULSATILE_DRUG_DELIVERY_SYSTEM_OF_ACECLOFENAC
The Chronopharmacotherapy the drug administration is synchronised with circadian rhythms Formulation development of Microspheres is more reliable formulation as compare to single type dosage formulation due to it avoids dose dumping, as per required
http://www.irjpbs.com/volumes/vol4/issue2/IRJPBS-4202.pdf
A combination of floating and pulsatile principles of drug delivery system would have the advantage that a drug can be released in upper GI tract after a defined time period of no drug release. A pulsatile drug delivery that can be administered at bed time but releases drug in early morning would be a promising chronotherapeutic system.
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2750381/
Oct 19, 2005 · The purpose of writing this review on floating drug delivery systems (FDDS) was to compile the recent literature with special focus on the principal mechanism of floatation to achieve gastric retention. The recent developments of FDDS including the physiological ...Author: Shweta Arora, Javed Ali, Alka Ahuja, Roop K. Khar, Sanjula Baboota
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